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    DRT111 D111/G-patch domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839927, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DRT111
    Official Full Name
    D111/G-patch domain-containing protein
    Primary source
    TAIR:AT1G30480
    Locus tag
    AT1G30480
    See related
    Araport:AT1G30480
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DNA-DAMAGE-REPAIR/TOLERATION PROTEIN 111; F26G16.10; F26G16_10; REQUIRED FOR SNC4-1D 2; RSN2
    Summary
    recombination and DNA-damage resistance protein (DRT111)
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    Genomic context

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    See DRT111 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (10790022..10792725)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene SIT4 phosphatase-associated family protein Neighboring gene Heavy metal transport/detoxification superfamily protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Homeobox-leucine zipper family protein / lipid-binding START domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two cDNAs from the plant Arabidopsis thaliana that partially restore recombination proficiency and DNA-damage resistance to E. coli mutants lacking recombination-intermediate-resolution activities. Pang Q, et al. Nucleic Acids Res, 1993 Apr 11. PMID 8479917, Free PMC Article
    2. SWAP1-SFPS-RRC1 splicing factor complex modulates pre-mRNA splicing to promote photomorphogenesis in Arabidopsis. Kathare PK, et al. Proc Natl Acad Sci U S A, 2022 Nov. PMID 36282917, Free PMC Article
    3. Splicing of receptor-like kinase-encoding SNC4 and CERK1 is regulated by two conserved splicing factors that are required for plant immunity. Zhang Z, et al. Mol Plant, 2014 Dec. PMID 25267732, Free PMC Article
    4. Drosophila SPF45: a bifunctional protein with roles in both splicing and DNA repair. Chaouki AS, et al. PLoS Genet, 2006 Dec 8. PMID 17154718, Free PMC Article
    5. High-throughput protein localization in Arabidopsis using Agrobacterium-mediated transient expression of GFP-ORF fusions. Koroleva OA, et al. Plant J, 2005 Jan. PMID 15610358

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. RSN2 encodes a splicing factor required for the alternative splicing of SNC4. RSN2 regulates alternative splicing of CERK1 and is required for PAMP-triggered immunity. [RSN2]
      Title: Splicing of receptor-like kinase-encoding SNC4 and CERK1 is regulated by two conserved splicing factors that are required for plant immunity.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_102784.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA repair IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in mRNA cis splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of RNA splicing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in cytoplasm HDA PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    D111/G-patch domain-containing protein
    NP_174336.1
    • DNA-DAMAGE-REPAIR/TOLERATION PROTEIN 111 (DRT111); FUNCTIONS IN: nucleotide binding, nucleic acid binding; INVOLVED IN: DNA repair; LOCATED IN: chloroplast, nucleus, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677), D111/G-patch (InterPro:IPR000467), Splicing factor, SPF45 (InterPro:IPR016967); Has 6802 Blast hits to 5609 proteins in 466 species: Archae - 14; Bacteria - 357; Metazoa - 3361; Fungi - 1024; Plants - 621; Viruses - 38; Other Eukaryotes - 1387 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      10790022..10792725
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102784.3 → NP_174336.1  D111/G-patch domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174336.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42698, Q9S9Q1
      UniProtKB/TrEMBL
      A0A178W6S6, A0A5S9WGX7, A0A654EJB5
      Conserved Domains (2) summary
      pfam01585
      Location:218 → 255
      G-patch; G-patch domain
      cd12647
      Location:281 → 377
      RRM_UHM_SPF45; RNA recognition motif (RRM) found in UHM domain of 45 kDa-splicing factor (SPF45) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P42698.2

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