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    ATPase E1-E2 type family protein / haloacid dehalogenase-like hydrolase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838324, updated on 18-Sep-2024

    Summary

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    Official Full Name
    ATPase E1-E2 type family protein / haloacid dehalogenase-like hydrolase family protein
    Primary source
    TAIR:AT1G17500
    Locus tag
    AT1G17500
    See related
    Araport:AT1G17500
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F1L3.21; F1L3_21
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    11
    Sequence:
    Chromosome: 1; NC_003070.9 (6017808..6023503)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene IQ-domain 7 Neighboring gene epidermal patterning factor-like protein Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene Homeodomain-like/winged-helix DNA-binding family protein Neighboring gene translocase of inner mitochondrial membrane 23

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Lipid Flippases ALA4 and ALA5 Play Critical Roles in Cell Expansion and Plant Growth. Davis JA, et al. Plant Physiol, 2020 Apr. PMID 32051180, Free PMC Article
    2. Arabidopsis Flippases Cooperate with ARF GTPase Exchange Factors to Regulate the Trafficking and Polarity of PIN Auxin Transporters. Zhang X, et al. Plant Cell, 2020 May. PMID 32193204, Free PMC Article
    3. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    4. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001332307.1
    NM_101612.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled intramembrane lipid transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables P-type ion transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in phospholipid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein localization involved in auxin polar transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ATPase E1-E2 type family protein / haloacid dehalogenase-like hydrolase family protein
    NP_001319028.1
    • ATPase E1-E2 type family protein / haloacid dehalogenase-like hydrolase family protein; FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; INVOLVED IN: metabolic process, ATP biosynthetic process, phospholipid transport; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, phospholipid-translocating, flippase (InterPro:IPR006539), ATPase, P-type, ATPase-associated domain (InterPro:IPR008250), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: ATPase E1-E2 type family protein / haloacid dehalogenase-like hydrolase family protein (TAIR:AT1G72700.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6017808..6023503
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001332307.1 → NP_001319028.1  ATPase E1-E2 type family protein / haloacid dehalogenase-like hydrolase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LNQ4
      UniProtKB/TrEMBL
      A0A178W5K3, A0A5S9UWX2
      Conserved Domains (1) summary
      TIGR01652
      Location:58 → 1151
      ATPase-Plipid; phospholipid-translocating P-type ATPase, flippase

    2. NM_101612.3 → NP_173193.2  ATPase E1-E2 type family protein / haloacid dehalogenase-like hydrolase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173193.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LNQ4
      UniProtKB/TrEMBL
      A0A178W5K3, A0A5S9UWX2
      Conserved Domains (1) summary
      TIGR01652
      Location:58 → 1151
      ATPase-Plipid; phospholipid-translocating P-type ATPase, flippase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LNQ4.2

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