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    CYCA3;4 CYCLIN A3;4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841126, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CYCA3;4
    Official Full Name
    CYCLIN A3;4
    Primary source
    TAIR:AT1G47230
    Locus tag
    AT1G47230
    See related
    Araport:AT1G47230
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CYCLIN A3;4; F8G22.5; F8G22_5
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    Genomic context

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    See CYCA3;4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Sequence:
    Chromosome: 1; NC_003070.9 (17306574..17308848)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene cyclin-dependent protein kinase 3;2 Neighboring gene Cyclin A3;3 Neighboring gene NRAMP metal ion transporter 2 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Cyclin CYCA3;4 Is a Postprophase Target of the APC/C(CCS52A2) E3-Ligase Controlling Formative Cell Divisions in Arabidopsis. Willems A, et al. Plant Cell, 2020 Sep. PMID 32690720, Free PMC Article
    2. Cyclin A participates in the TSO1-MYB3R1 regulatory module to maintain shoot meristem size and fertility in Arabidopsis. Wang F, et al. Development, 2023 Mar 1. PMID 36805640
    3. Arabidopsis anaphase-promoting complexes: multiple activators and wide range of substrates might keep APC perpetually busy. Fülöp K, et al. Cell Cycle, 2005 Aug. PMID 15970679
    4. Functional modules in the Arabidopsis core cell cycle binary protein-protein interaction network. Boruc J, et al. Plant Cell, 2010 Apr. PMID 20407024, Free PMC Article
    5. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Cyclin A participates in the TSO1-MYB3R1 regulatory module to maintain shoot meristem size and fertility in Arabidopsis.
      Title: Cyclin A participates in the TSO1-MYB3R1 regulatory module to maintain shoot meristem size and fertility in Arabidopsis.
    2. The Cyclin CYCA3;4 Is a Postprophase Target of the APC/C(CCS52A2) E3-Ligase Controlling Formative Cell Divisions in Arabidopsis.
      Title: The Cyclin CYCA3;4 Is a Postprophase Target of the APC/C(CCS52A2) E3-Ligase Controlling Formative Cell Divisions in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_103617.4
    NM_202254.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic cell cycle phase transition IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CYCLIN A3;4
    NP_175156.1
    • CYCLIN A3;4 (CYCA3;4); FUNCTIONS IN: cyclin-dependent protein kinase regulator activity; INVOLVED IN: regulation of cell cycle; LOCATED IN: nucleus; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Cyclin, C-terminal (InterPro:IPR004367), Cyclin (InterPro:IPR006670), G2/mitotic-specific cyclin A (InterPro:IPR015453), Cyclin-like (InterPro:IPR011028), Cyclin-related (InterPro:IPR013763), Cyclin, N-terminal (InterPro:IPR006671), Cyclin, A/B/D/E (InterPro:IPR014400); BEST Arabidopsis thaliana protein match is: cyclin-dependent protein kinase 3;2 (TAIR:AT1G47210.2); Has 4301 Blast hits to 4300 proteins in 367 species: Archae - 0; Bacteria - 0; Metazoa - 1966; Fungi - 532; Plants - 1110; Viruses - 34; Other Eukaryotes - 659 (source: NCBI BLink).
    NP_973983.1
    • CYCLIN A3;4 (CYCA3;4); FUNCTIONS IN: cyclin-dependent protein kinase regulator activity; INVOLVED IN: regulation of cell cycle; LOCATED IN: nucleus; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Cyclin, C-terminal (InterPro:IPR004367), G2/mitotic-specific cyclin A (InterPro:IPR015453), Cyclin-like (InterPro:IPR011028), Cyclin-related (InterPro:IPR013763), Cyclin, N-terminal (InterPro:IPR006671), Cyclin, A/B/D/E (InterPro:IPR014400), Cyclin (InterPro:IPR006670); BEST Arabidopsis thaliana protein match is: cyclin-dependent protein kinase 3;2 (TAIR:AT1G47210.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      17306574..17308848
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103617.4 → NP_175156.1  CYCLIN A3;4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175156.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W2K2, A0A5S9WMU1, A0A654EGE7
      Conserved Domains (2) summary
      cd20506
      Location:229 → 343
      CYCLIN_AtCycA-like_rpt2; second cyclin box found in Arabidopsis thaliana A-type cyclins (CycAs) and similar proteins
      cd20562
      Location:88 → 225
      CYCLIN_AtCycA_like_rpt1; first cyclin box found in Arabidopsis thaliana A-type cyclins (CycAs) and similar proteins

    2. NM_202254.2 → NP_973983.1  CYCLIN A3;4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973983.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3ECW2, Q9C6B1
      UniProtKB/TrEMBL
      A0A178W490
      Conserved Domains (2) summary
      cd20506
      Location:230 → 344
      CYCLIN_AtCycA-like_rpt2; second cyclin box found in Arabidopsis thaliana A-type cyclins (CycAs) and similar proteins
      cd20562
      Location:88 → 226
      CYCLIN_AtCycA_like_rpt1; first cyclin box found in Arabidopsis thaliana A-type cyclins (CycAs) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3ECW2.1

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