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    TPX2 (targeting protein for Xklp2) protein family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821318, updated on 18-Sep-2024

    Summary

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    Official Full Name
    TPX2 (targeting protein for Xklp2) protein family
    Primary source
    TAIR:AT3G01015
    Locus tag
    AT3G01015
    See related
    Araport:AT3G01015
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    TEL3N.1; TEL3N_1
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    8
    Sequence:
    Chromosome: 3; NC_003074.8 (1609..4159, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene UDP-glucose/GDP-mannose dehydrogenase family protein Neighboring gene ISCU-like 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Submergence stress-induced hypocotyl elongation through ethylene signaling-mediated regulation of cortical microtubules in Arabidopsis. Wang X, et al. J Exp Bot, 2020 Jan 23. PMID 31638649
    2. Coordinated Regulation of Hypocotyl Cell Elongation by Light and Ethylene through a Microtubule Destabilizing Protein. Ma Q, et al. Plant Physiol, 2018 Jan. PMID 29167353, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Submergence stress-induced hypocotyl elongation through ethylene signaling-mediated regulation of cortical microtubules in Arabidopsis.
      Title: Submergence stress-induced hypocotyl elongation through ethylene signaling-mediated regulation of cortical microtubules in Arabidopsis.
    2. This study reveals a mechanism in which light and ethylene signaling coordinate MDP60 expression to modulate hypocotyl cell elongation by altering cortical microtubules in Arabidopsis.[Mdp60]
      Title: Coordinated Regulation of Hypocotyl Cell Elongation by Light and Ethylene through a Microtubule Destabilizing Protein.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_110965.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables microtubule binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cortical microtubule organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within cortical microtubule organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cortical microtubule organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within microtubule depolymerization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of mitotic spindle organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of plant organ morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to ethylene IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to light stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to water-immersion restraint stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to water-immersion restraint stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    colocalizes_with microtubule end IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in spindle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    TPX2 (targeting protein for Xklp2) protein family
    NP_186749.2
    • TPX2 (targeting protein for Xklp2) protein family; CONTAINS InterPro DOMAIN/s: Xklp2 targeting protein (InterPro:IPR009675); BEST Arabidopsis thaliana protein match is: TPX2 (targeting protein for Xklp2) protein family (TAIR:AT5G15510.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      1609..4159 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_110965.4 → NP_186749.2  TPX2 (targeting protein for Xklp2) protein family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_186749.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A178VFR0, Q5XVC4, Q9C7U3
      UniProtKB/TrEMBL
      A0A384K930
      Conserved Domains (1) summary
      pfam06886
      Location:374 → 455
      TPX2; Targeting protein for Xklp2 (TPX2)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XVC4.1

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