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    CDG1 Protein kinase superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822312, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CDG1
    Official Full Name
    Protein kinase superfamily protein
    Primary source
    TAIR:AT3G26940
    Locus tag
    AT3G26940
    See related
    Araport:AT3G26940
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CONSTITUTIVE DIFFERENTIAL GROWTH 1
    Summary
    Receptor-like cytoplasmic kinase, RLCKVII subfamily. Overexpression causes abnormal differential and elongation growth after organ differentiation.
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    Genomic context

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    See CDG1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (9936582..9939305, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene dsRNA-binding protein 3 Neighboring gene DHHC-type zinc finger family protein Neighboring gene uncharacterized protein Neighboring gene Pollen Ole e 1 allergen and extensin family protein Neighboring gene membrane-anchored ubiquitin-fold protein 4 precursor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Overexpression of constitutive differential growth 1 gene, which encodes a RLCKVII-subfamily protein kinase, causes abnormal differential and elongation growth after organ differentiation in Arabidopsis. Muto H, et al. Plant Physiol, 2004 Oct. PMID 15466232, Free PMC Article
    2. The receptor-like cytoplasmic kinase CDG1 negatively regulates Arabidopsis pattern-triggered immunity and is involved in AvrRpm1-induced RIN4 phosphorylation. Yang Q, et al. Plant Cell, 2021 May 31. PMID 33619522
    3. The CDG1 kinase mediates brassinosteroid signal transduction from BRI1 receptor kinase to BSU1 phosphatase and GSK3-like kinase BIN2. Kim TW, et al. Mol Cell, 2011 Aug 19. PMID 21855796, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The receptor-like cytoplasmic kinase CDG1 negatively regulates Arabidopsis pattern-triggered immunity and is involved in AvrRpm1-induced RIN4 phosphorylation.
      Title: The receptor-like cytoplasmic kinase CDG1 negatively regulates Arabidopsis pattern-triggered immunity and is involved in AvrRpm1-induced RIN4 phosphorylation.
    2. CDG1 mediates signal transduction from BRI1 to BSU1.
      Title: The CDG1 kinase mediates brassinosteroid signal transduction from BRI1 receptor kinase to BSU1 phosphatase and GSK3-like kinase BIN2.
    3. CDG1 gene may interfere with signal transduction of BR when overexpressed, but is not an essential factor for it in the wild type. [CDG1]
      Title: Overexpression of constitutive differential growth 1 gene, which encodes a RLCKVII-subfamily protein kinase, causes abnormal differential and elongation growth after organ differentiation in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_113608.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of brassinosteroid mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Protein kinase superfamily protein
    NP_189330.1
    • CONSTITUTIVE DIFFERENTIAL GROWTH 1 (CDG1); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: growth; EXPRESSED IN: flower; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT5G13160.1); Has 115206 Blast hits to 113810 proteins in 4116 species: Archae - 109; Bacteria - 12984; Metazoa - 42968; Fungi - 9463; Plants - 32819; Viruses - 350; Other Eukaryotes - 16513 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      9936582..9939305 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113608.3 → NP_189330.1  Protein kinase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189330.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0MEY6, Q84UJ3, Q9LSE1
      UniProtKB/TrEMBL
      A0A178VIM3, A0A5S9XHL5
      Conserved Domains (1) summary
      cd14066
      Location:80 → 352
      STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LSE1.1

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