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    COX17 cytochrome c oxidase 17 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820770, updated on 18-Sep-2024

    Summary

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    Official Symbol
    COX17
    Official Full Name
    cytochrome c oxidase 17
    Primary source
    TAIR:AT3G15352
    Locus tag
    AT3G15352
    See related
    Araport:AT3G15352
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA CYTOCHROME C OXIDASE 17; ATCOX17; cytochrome c oxidase 17
    Summary
    Encodes protein similar to yeast COX17, a copper-binding protein that mediates the delivery of Cu to the mitochondria for the assembly of a functional cytochrome oxidase complex.
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    Genomic context

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    See COX17 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (5179358..5180665)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene P53/DNA damage-regulated protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene metallothionein 3 Neighboring gene ubiquitin-conjugating enzyme 25

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The cytochrome c oxidase biogenesis factor AtCOX17 modulates stress responses in Arabidopsis. Garcia L, et al. Plant Cell Environ, 2016 Mar. PMID 26436309
    2. AtCOX17, an Arabidopsis homolog of the yeast copper chaperone COX17. Balandin T, et al. Plant Physiol, 2002 Aug. PMID 12177498, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_001338158.1
    NM_001338159.1
    NM_001338160.1
    NM_112400.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables copper chaperone activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables copper chaperone activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables copper ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to copper ion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome c oxidase 17
    NP_566508.1
    • cytochrome c oxidase 17 (COX17); FUNCTIONS IN: copper chaperone activity; INVOLVED IN: response to bacterium, response to copper ion; LOCATED IN: mitochondrial intermembrane space; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome c oxidase copper chaperone (InterPro:IPR007745); BEST Arabidopsis thaliana protein match is: Cytochrome C oxidase copper chaperone (COX17) (TAIR:AT1G53030.1); Has 294 Blast hits to 294 proteins in 132 species: Archae - 0; Bacteria - 0; Metazoa - 138; Fungi - 51; Plants - 55; Viruses - 0; Other Eukaryotes - 50 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5179358..5180665
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112400.3 → NP_566508.1  cytochrome c oxidase 17 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566508.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LJQ9
      UniProtKB/TrEMBL
      A0A178V986, A0A5S9XCW7
      Conserved Domains (1) summary
      pfam05051
      Location:29 → 74
      COX17; Cytochrome C oxidase copper chaperone (COX17)

    2. NM_001338158.1 → NP_001327630.1  cytochrome c oxidase 17 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LSX2
      Conserved Domains (1) summary
      pfam05051
      Location:30 → 75
      COX17; Cytochrome C oxidase copper chaperone (COX17)

    3. NM_001338159.1 → NP_001327631.1  cytochrome c oxidase 17 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LSX3

    4. NM_001338160.1 → NP_001327629.1  cytochrome c oxidase 17 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LSX1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LJQ9.1

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