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    Protein with RING/U-box and TRAF-like domain [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842983, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Protein with RING/U-box and TRAF-like domain
    Primary source
    TAIR:AT1G66650
    Locus tag
    AT1G66650
    See related
    Araport:AT1G66650
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (24859917..24861821, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Protein with RING/U-box and TRAF-like domain Neighboring gene RNI-like superfamily protein Neighboring gene Protein with RING/U-box and TRAF-like domain Neighboring gene CLP protease proteolytic subunit 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of Arabidopsis SUMO-interacting proteins that regulate chromatin activity and developmental transitions. Elrouby N, et al. Proc Natl Acad Sci U S A, 2013 Dec 3. PMID 24255109, Free PMC Article
    2. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_179522.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables SUMO binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within vegetative to reproductive phase transition of meristem IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Protein with RING/U-box and TRAF-like domain
    NP_849853.1
    • Protein with RING/U-box and TRAF-like domains; FUNCTIONS IN: ubiquitin-protein ligase activity, zinc ion binding; INVOLVED IN: multicellular organismal development, protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: intracellular, nucleus; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), TRAF-like (InterPro:IPR008974), Seven-in-absentia protein, TRAF-like domain (InterPro:IPR018121), Zinc finger, SIAH-type (InterPro:IPR013010), Seven In Absentia Homolog-type (InterPro:IPR013323), Seven-in-absentia protein, sina (InterPro:IPR004162); BEST Arabidopsis thaliana protein match is: Protein with RING/U-box and TRAF-like domains (TAIR:AT5G37930.1); Has 1538 Blast hits to 1533 proteins in 685 species: Archae - 0; Bacteria - 0; Metazoa - 1019; Fungi - 2; Plants - 466; Viruses - 2; Other Eukaryotes - 49 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      24859917..24861821 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179522.2 → NP_849853.1  Protein with RING/U-box and TRAF-like domain [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849853.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C6H0, Q9C9M0
      UniProtKB/TrEMBL
      A0A178WAM0, A0A5S9WQD5
      Conserved Domains (2) summary
      cl17238
      Location:84 → 122
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
      cl19105
      Location:128 → 209
      Sina; Seven in absentia (Sina) protein family, C-terminal substrate binding domain; composed of the Drosophila Sina protein, the mammalian Sina homolog (Siah), the plant protein SINAT5, and similar proteins. Sina, Siah and SINAT5 are RING-containing proteins ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C9M0.1

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