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    UNE12 basic helix-loop-helix (bHLH) DNA-binding superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828126, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UNE12
    Official Full Name
    basic helix-loop-helix (bHLH) DNA-binding superfamily protein
    Primary source
    TAIR:AT4G02590
    Locus tag
    AT4G02590
    See related
    Araport:AT4G02590
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T10P11.13; T10P11_13; unfertilized embryo sac 12
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    Genomic context

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    See UNE12 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Sequence:
    Chromosome: 4; NC_003075.7 (1137487..1140540, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene cullin 1 Neighboring gene NADH-ubiquinone oxidoreductase 24 kDa subunit Neighboring gene ncRNA Neighboring gene Seven transmembrane MLO family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. UNFERTILIZED EMBRYO SAC 12 phosphorylation plays a crucial role in conferring salt tolerance. He Z, et al. Plant Physiol, 2022 Feb 4. PMID 34904673, Free PMC Article
    2. Natural variation in temperature-modulated immunity uncovers transcription factor bHLH059 as a thermoresponsive regulator in Arabidopsis thaliana. Bruessow F, et al. PLoS Genet, 2021 Jan. PMID 33493201, Free PMC Article
    3. Two types of bHLH transcription factor determine the competence of the pericycle for lateral root initiation. Zhang Y, et al. Nat Plants, 2021 May. PMID 34007039
    4. Independently evolved virulence effectors converge onto hubs in a plant immune system network. Mukhtar MS, et al. Science, 2011 Jul 29. PMID 21798943, Free PMC Article
    5. A stele-enriched gene regulatory network in the Arabidopsis root. Brady SM, et al. Mol Syst Biol, 2011 Jan 18. PMID 21245844, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001036500.2
    NM_001125447.1
    NM_116493.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within double fertilization forming a zygote and endosperm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of defense response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of gene expression IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of salicylic acid mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to abscisic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to osmotic stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to salt IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    basic helix-loop-helix (bHLH) DNA-binding superfamily protein
    NP_001031577.1
    • unfertilized embryo sac 12 (UNE12); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: double fertilization forming a zygote and endosperm, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT1G03040.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_001118919.1
    • unfertilized embryo sac 12 (UNE12); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: double fertilization forming a zygote and endosperm, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT1G03040.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_567245.1
    • unfertilized embryo sac 12 (UNE12); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: double fertilization forming a zygote and endosperm, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT1G03040.1); Has 2959 Blast hits to 2953 proteins in 110 species: Archae - 0; Bacteria - 0; Metazoa - 29; Fungi - 7; Plants - 2922; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      1137487..1140540 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116493.3 → NP_567245.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567245.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H4J4, O22768, Q8L9U3, Q8S3E3
      UniProtKB/TrEMBL
      A0A178UUM2, A0A384KS03, A0A5S9XPJ7, B9DFF4
      Conserved Domains (1) summary
      cl00081
      Location:146 → 210
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    2. NM_001125447.1 → NP_001118919.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001118919.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22768

    3. NM_001036500.2 → NP_001031577.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031577.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H4J4, O22768, Q8L9U3, Q8S3E3
      UniProtKB/TrEMBL
      A0A178UUM2, A0A384KS03, A0A5S9XPJ7, B9DFF4
      Conserved Domains (1) summary
      cl00081
      Location:146 → 210
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22768.2

    Gene LinkOut

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