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    PAO5 polyamine oxidase 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829093, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PAO5
    Official Full Name
    polyamine oxidase 5
    Primary source
    TAIR:AT4G29720
    Locus tag
    AT4G29720
    See related
    Araport:AT4G29720
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtPAO5; ATPAO5; polyamine oxidase 5; T16L4.230; T16L4_230
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    Genomic context

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    See PAO5 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    1
    Sequence:
    Chromosome: 4; NC_003075.7 (14553211..14555276, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Alkaline-phosphatase-like family protein Neighboring gene nucleosome/chromatin assembly factor group C5 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis polyamine oxidase/dehydrogenase 5 interferes with cytokinin and auxin signaling pathways to control xylem differentiation. Alabdallah O, et al. J Exp Bot, 2017 Feb 1. PMID 28199662
    2. Polyamine oxidase 5 loss-of-function mutations in Arabidopsis thaliana trigger metabolic and transcriptional reprogramming and promote salt stress tolerance. Zarza X, et al. Plant Cell Environ, 2017 Apr. PMID 26791972
    3. POLYAMINE OXIDASE 1 from rice (Oryza sativa) is a functional ortholog of Arabidopsis POLYAMINE OXIDASE 5. Liu T, et al. Plant Signal Behav, 2014. PMID 25763711, Free PMC Article
    4. Polyamine Oxidase5 Regulates Arabidopsis Growth through Thermospermine Oxidase Activity. Kim DW, et al. Plant Physiol, 2014 Aug. PMID 24906355, Free PMC Article
    5. A plant spermine oxidase/dehydrogenase regulated by the proteasome and polyamines. Ahou A, et al. J Exp Bot, 2014 Apr. PMID 24550437

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Two independent loss-of-function mutants (atpao5-2 and atpao5-3) were found to exhibit constitutively higher thermospermine levels, with associated increased salt tolerance.
      Title: Polyamine oxidase 5 loss-of-function mutations in Arabidopsis thaliana trigger metabolic and transcriptional reprogramming and promote salt stress tolerance.
    2. AtPAO5, being involved in the control of Therm-Spm homeostasis, participates in the tightly controlled interplay between auxin and cytokinins that is necessary for proper xylem differentiation.
      Title: The Arabidopsis polyamine oxidase/dehydrogenase 5 interferes with cytokinin and auxin signaling pathways to control xylem differentiation.
    3. results suggest that rice PAO1 is the functional ortholog of Arabidopsis PAO5
      Title: POLYAMINE OXIDASE 1 from rice (Oryza sativa) is a functional ortholog of Arabidopsis POLYAMINE OXIDASE 5.
    4. AtPAO5 is a cytosolic protein undergoing proteasomal control. Positive regulation of AtPAO5 expression by polyamines is at the transcriptional and post-transcriptional level.
      Title: A plant spermine oxidase/dehydrogenase regulated by the proteasome and polyamines.
    5. flavin amine oxidase (FAO1) affects shoot regeneration by regulating cellular polyamines. [FAO1]
      Title: Cloning and characterization of Arabidopsis and Brassica juncea flavin-containing amine oxidases.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_119117.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables thermospermine oxidase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of timing of transition from vegetative to reproductive phase IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in spermine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    polyamine oxidase 5
    NP_194701.1
    • polyamine oxidase 5 (PAO5); FUNCTIONS IN: primary amine oxidase activity; LOCATED IN: endomembrane system; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Amine oxidase (InterPro:IPR002937); BEST Arabidopsis thaliana protein match is: LSD1-like 3 (TAIR:AT4G16310.1); Has 3107 Blast hits to 2713 proteins in 458 species: Archae - 2; Bacteria - 686; Metazoa - 1027; Fungi - 508; Plants - 550; Viruses - 0; Other Eukaryotes - 334 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      14553211..14555276 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119117.2 → NP_194701.1  polyamine oxidase 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194701.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SU79
      UniProtKB/TrEMBL
      A0A5S9XXH1, A0A654FU16
      Conserved Domains (3) summary
      PLN02568
      Location:1 → 533
      PLN02568; polyamine oxidase
      pfam13450
      Location:9 → 77
      NAD_binding_8; NAD(P)-binding Rossmann-like domain
      cl21454
      Location:251 → 288
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SU79.1

    Gene LinkOut

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