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    BAP1 BON association protein 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825291, updated on 18-Sep-2024

    Summary

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    Official Symbol
    BAP1
    Official Full Name
    BON association protein 1
    Primary source
    TAIR:AT3G61190
    Locus tag
    AT3G61190
    See related
    Araport:AT3G61190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    BON association protein 1
    Summary
    Encodes a protein with a C2 domain that binds to BON1 in yeast two hybrid analyses. Its ability to bind to phospholipids is enhanced by calcium ions. Involved in maintaining cell homeostasis.
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    Genomic context

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    See BAP1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (22650159..22651636, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene low-molecular-weight cysteine-rich 54 Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene Thioesterase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The C2 domain protein BAP1 negatively regulates defense responses in Arabidopsis. Yang H, et al. Plant J, 2006 Oct. PMID 17018034
    2. Induction of BAP1 by a moderate decrease in temperature is mediated by ICE1 in Arabidopsis. Zhu Y, et al. Plant Physiol, 2011 Jan. PMID 21098676, Free PMC Article
    3. Requirement of calcium binding, myristoylation, and protein-protein interaction for the Copine BON1 function in Arabidopsis. Li Y, et al. J Biol Chem, 2010 Sep 24. PMID 20634289, Free PMC Article
    4. Plant growth homeostasis is controlled by the Arabidopsis BON1 and BAP1 genes. Hua J, et al. Genes Dev, 2001 Sep 1. PMID 11544183, Free PMC Article
    5. The Arabidopsis BAP1 and BAP2 genes are general inhibitors of programmed cell death. Yang H, et al. Plant Physiol, 2007 Sep. PMID 17631528, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The inducer of CBF expression1 (ICE1) protein that is involved in transcriptional control of cold responses is found to bind to a MYC element in this BAP1 promoter and is required for the cooling induction of BAP1.
      Title: Induction of BAP1 by a moderate decrease in temperature is mediated by ICE1 in Arabidopsis.
    2. general inhibitor of programmed cell death, expression in yeast alleviates cell death induced by hydrogen peroxide
      Title: The Arabidopsis BAP1 and BAP2 genes are general inhibitors of programmed cell death.
    3. The BAP1 protein functions together with an evolutionarily conserved C2 domain protein BON1/CPN1 to negatively regulate defense responses in plants.
      Title: The C2 domain protein BAP1 negatively regulates defense responses in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001203221.2
    NM_115983.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phospholipid binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular homeostasis IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of defense response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salicylic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to temperature stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to wounding IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    BON association protein 1
    NP_001190150.2
    • BON association protein 1 (BAP1); FUNCTIONS IN: phospholipid binding, protein binding; INVOLVED IN: in 7 processes; LOCATED IN: membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: BON association protein 2 (TAIR:AT2G45760.1).
    NP_567111.1
    • BON association protein 1 (BAP1); FUNCTIONS IN: phospholipid binding, protein binding; INVOLVED IN: in 7 processes; LOCATED IN: membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: BON association protein 2 (TAIR:AT2G45760.1); Has 85 Blast hits to 85 proteins in 15 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 85; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      22650159..22651636 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001203221.2 → NP_001190150.2  BON association protein 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LBT3, Q941L2, Q9M2E5
      UniProtKB/TrEMBL
      A0A178VLX1, A0A5S9XN00, A0A654FJQ6, F4JE67
      Conserved Domains (1) summary
      cd04051
      Location:19 → 137
      C2_SRC2_like; C2 domain present in Soybean genes Regulated by Cold 2 (SRC2)-like proteins

    2. NM_115983.3 → NP_567111.1  BON association protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567111.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LBT3, Q941L2, Q9M2E5
      UniProtKB/TrEMBL
      A0A178VLX1, A0A5S9XN00, A0A654FJQ6, F4JE67
      Conserved Domains (1) summary
      cd04051
      Location:19 → 137
      C2_SRC2_like; C2 domain present in Soybean genes Regulated by Cold 2 (SRC2)-like proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q941L2.1

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