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    HTA12 histone H2A 12 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831891, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HTA12
    Official Full Name
    histone H2A 12
    Primary source
    TAIR:AT5G02560
    Locus tag
    AT5G02560
    See related
    Araport:AT5G02560
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    histone H2A 12; T22P11.150; T22P11_150
    Summary
    Encodes HTA12, a histone H2A protein.
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    Genomic context

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    See HTA12 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (575225..577216)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene uncharacterized protein Neighboring gene Histone superfamily protein Neighboring gene argininosuccinate lyase Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The histone variant H2A.W defines heterochromatin and promotes chromatin condensation in Arabidopsis. Yelagandula R, et al. Cell, 2014 Jul 3. PMID 24995981, Free PMC Article
    2. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001203279.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within heterochromatin organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    histone H2A 12
    NP_001190208.1
    • histone H2A 12 (HTA12); FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleus, nucleosome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: histone H2A 6 (TAIR:AT5G59870.1).
    NP_195876.1
    • histone H2A 12 (HTA12); FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleus, nucleosome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: histone H2A 6 (TAIR:AT5G59870.1); Has 3926 Blast hits to 3921 proteins in 369 species: Archae - 0; Bacteria - 0; Metazoa - 2576; Fungi - 297; Plants - 619; Viruses - 2; Other Eukaryotes - 432 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      575225..577216
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120334.3 → NP_195876.1  histone H2A 12 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195876.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LZ46
      UniProtKB/TrEMBL
      A0A178UDS9, A0A384LGA5, Q1H552
      Conserved Domains (1) summary
      PLN00157
      Location:20 → 140
      PLN00157; histone H2A; Provisional

    2. NM_001203279.1 → NP_001190208.1  histone H2A 12 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190208.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4KCF4
      Conserved Domains (2) summary
      PLN00157
      Location:20 → 164
      PLN00157; histone H2A; Provisional
      cd00074
      Location:20 → 153
      H2A; Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LZ46.1

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