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    FLA11 FASCICLIN-like arabinogalactan-protein 11 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831914, updated on 18-Sep-2024

    Summary

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    Official Symbol
    FLA11
    Official Full Name
    FASCICLIN-like arabinogalactan-protein 11
    Primary source
    TAIR:AT5G03170
    Locus tag
    AT5G03170
    See related
    Araport:AT5G03170
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS FASCICLIN-LIKE ARABINOGALACTAN-PROTEIN 11; ATFLA11; F15A17.200; F15A17_200; FASCICLIN-like arabinogalactan-protein 11
    Summary
    Encodes FLA11, a member of fasciclin-like arabinogalactan proteins (FLAs) containing a cell adhesion fasciclin (FAS) domain. Mutations result in altered stem biomechanics with reduced tensile strength and reduced tensile modulus of elasticity, as well as altered cell wall architecture and composition, with increased cellulose microfibril angle, reduced arabinose, galactose and cellulose content.
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    Genomic context

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    See FLA11 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (752750..753657, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Concanavalin A-like lectin protein kinase family protein Neighboring gene C2H2-like zinc finger protein Neighboring gene DnaJ P58IPK-like protein Neighboring gene RING/U-box superfamily protein Neighboring gene ncRNA Neighboring gene peptide upstream protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Distinct functions of FASCILIN-LIKE ARABINOGALACTAN PROTEINS relate to domain structure. Ma Y, et al. Plant Physiol, 2023 May 2. PMID 36797772, Free PMC Article
    2. AtFLA11, a fasciclin-like arabinogalactan-protein, specifically localized in sclerenchyma cells. Ito S, et al. Biosci Biotechnol Biochem, 2005 Oct. PMID 16244449
    3. FLA11 and FLA12 glycoproteins fine-tune stem secondary wall properties in response to mechanical stresses. Ma Y, et al. New Phytol, 2022 Feb. PMID 34862967, Free PMC Article
    4. Fasciclin-like arabinogalactan proteins: specialization for stem biomechanics and cell wall architecture in Arabidopsis and Eucalyptus. MacMillan CP, et al. Plant J, 2010 May 1. PMID 20202165
    5. An integrative approach to the identification of Arabidopsis and rice genes involved in xylan and secondary wall development. Oikawa A, et al. PLoS One, 2010 Nov 23. PMID 21124849, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. FLA11 and FLA12 glycoproteins fine-tune stem secondary wall properties in response to mechanical stresses.
      Title: FLA11 and FLA12 glycoproteins fine-tune stem secondary wall properties in response to mechanical stresses.
    2. fluctuation of AtFLA11 transcripts during the maturation process of sclerenchyma cells suggests its role in the formation of the secondary cell wall
      Title: AtFLA11, a fasciclin-like arabinogalactan-protein, specifically localized in sclerenchyma cells.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_120395.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within plant-type secondary cell wall biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of secondary cell wall biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to mechanical stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 
    is_active_in plant-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in secondary cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    FASCICLIN-like arabinogalactan-protein 11
    NP_195937.1
    • FASCICLIN-like arabinogalactan-protein 11 (FLA11); CONTAINS InterPro DOMAIN/s: FAS1 domain (InterPro:IPR000782); BEST Arabidopsis thaliana protein match is: FASCICLIN-like arabinogalactan-protein 12 (TAIR:AT5G60490.1); Has 965 Blast hits to 948 proteins in 162 species: Archae - 18; Bacteria - 233; Metazoa - 22; Fungi - 18; Plants - 634; Viruses - 0; Other Eukaryotes - 40 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      752750..753657 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120395.2 → NP_195937.1  FASCICLIN-like arabinogalactan-protein 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195937.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LEJ6, Q9LYW8
      UniProtKB/TrEMBL
      A0A178UN19, A0A5S9Y175
      Conserved Domains (1) summary
      pfam02469
      Location:45 → 181
      Fasciclin; Fasciclin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LEJ6.2

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