ATB' ALPHA Protein phosphatase 2A regulatory B subunit family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ATB' ALPHA
Official Full Name: Protein phosphatase 2A regulatory B subunit family protein
Primary source: TAIR:AT5G03470
Locus tag: AT5G03470
See related: Araport:AT5G03470
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F12E4.240; F12E4_240
Summary: Encodes B' regulatory subunit of PP2A (AtB'alpha), putative size of 57 kDa.
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Genomic context

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See ATB' ALPHA in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 2

Sequence:: Chromosome: 5; NC_003076.8 (866339..869252)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The combined absence of the regulatory subunits protein phosphatase 2A (PP2AB'alpha and PP2AB'beta) leads to the premature loss of chromosome cohesion in meiosis I.
Title: PROTEIN PHOSHATASE 2A B'α and β Maintain Centromeric Sister Chromatid Cohesion during Meiosis in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_120427.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein phosphatase regulator activity	IEA Inferred from Electronic Annotation more info
enables protein phosphatase regulator activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within megasporogenesis	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within meiotic sister chromatid cohesion	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within microsporogenesis	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within regulation of phosphorylation	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
colocalizes_with condensed chromosome, centromeric region	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
part_of protein phosphatase type 2A complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed

General protein information

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Preferred Names: Protein phosphatase 2A regulatory B subunit family protein

NP_195967.1

ATB' ALPHA; CONTAINS InterPro DOMAIN/s: Protein phosphatase 2A, regulatory B subunit, B56 (InterPro:IPR002554); BEST Arabidopsis thaliana protein match is: Protein phosphatase 2A regulatory B subunit family protein (TAIR:AT3G09880.1); Has 1194 Blast hits to 1162 proteins in 195 species: Archae - 0; Bacteria - 0; Metazoa - 571; Fungi - 171; Plants - 302; Viruses - 0; Other Eukaryotes - 150 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

866339..869252

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_120427.3 → NP_195967.1 Protein phosphatase 2A regulatory B subunit family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_195967.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O04375

UniProtKB/TrEMBL

A0A178UNX1, A0A5S9Y121

Conserved Domains (2) summary

pfam01603
Location:79 → 482

B56; Protein phosphatase 2A regulatory B subunit (B56 family)

cl27532
Location:28 → 91

B56; Protein phosphatase 2A regulatory B subunit (B56 family)