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    Mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832536, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein
    Primary source
    TAIR:AT5G24650
    Locus tag
    AT5G24650
    See related
    Araport:AT5G24650
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    HP30-2; hypothetical protein 30-2; K18P6.19; K18P6_19
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (8437024..8439104)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Pathogenesis-related thaumatin superfamily protein Neighboring gene ncRNA Neighboring gene double-stranded DNA binding protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene response to low sulfur 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. HP30-2, a mitochondrial PRAT protein for import of signal sequence-less precursor proteins in Arabidopsis thaliana. Rossig C, et al. J Integr Plant Biol, 2017 Aug. PMID 28544763
    2. Plant-Specific Preprotein and Amino Acid Transporter Proteins Are Required for tRNA Import into Mitochondria. Murcha MW, et al. Plant Physiol, 2016 Dec. PMID 27789739, Free PMC Article
    3. Characterization of the preprotein and amino acid transporter gene family in Arabidopsis. Murcha MW, et al. Plant Physiol, 2007 Jan. PMID 17098851, Free PMC Article
    4. PRAT Proteins Operate in Organellar Protein Import and Export in Arabidopsis thaliana. Rossig C, et al. Plants (Basel), 2021 May 11. PMID 34064964, Free PMC Article
    5. Three proteins mediate import of transit sequence-less precursors into the inner envelope of chloroplasts in Arabidopsis thaliana. Rossig C, et al. Proc Natl Acad Sci U S A, 2013 Dec 3. PMID 24248378, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_122373.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within mitochondrion organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in protein insertion into mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein targeting to chloroplast IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within tRNA import into mitochondrion IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of TIM22 mitochondrial import inner membrane insertion complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of TIM23 mitochondrial import inner membrane translocase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plastid HDA PubMed 
    located_in vacuole HDA PubMed 

    General protein information

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    Preferred Names
    Mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein
    NP_197853.1
    • Mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein; FUNCTIONS IN: protein transporter activity, P-P-bond-hydrolysis-driven protein transmembrane transporter activity; INVOLVED IN: protein transport; LOCATED IN: chloroplast, plasma membrane, vacuole, mitochondrial inner membrane presequence translocase complex, chloroplast envelope; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Sterile alpha motif, type 1 (InterPro:IPR021129), Mitochondrial inner membrane translocase complex, subunit Tim17/22 (InterPro:IPR003397); BEST Arabidopsis thaliana protein match is: Mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein (TAIR:AT3G49560.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      8437024..8439104
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122373.3 → NP_197853.1  Mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197853.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L9N9, Q9FLT9
      UniProtKB/TrEMBL
      A0A178UF81, A0A5S9Y7H4
      Conserved Domains (2) summary
      cd09487
      Location:196 → 247
      SAM_superfamily; SAM (Sterile alpha motif )
      pfam02466
      Location:50 → 170
      Tim17; Tim17/Tim22/Tim23/Pmp24 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FLT9.1

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