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    DCD (Development and Cell Death) domain protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834210, updated on 18-Sep-2024

    Summary

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    Official Full Name
    DCD (Development and Cell Death) domain protein
    Primary source
    TAIR:AT5G42050
    Locus tag
    AT5G42050
    See related
    Araport:AT5G42050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MJC20.15; MJC20_15
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (16815310..16817346)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ABL interactor-like protein 4 Neighboring gene regulatory particle non-ATPase 12B Neighboring gene uncharacterized protein Neighboring gene DEK, chromatin associated protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Investigations on N-rich protein (NRP) of Arabidopsis thaliana under different stress conditions. Hoepflinger MC, et al. Plant Physiol Biochem, 2011 Mar. PMID 21277785
    2. Abscisic acid employs NRP-dependent PIN2 vacuolar degradation to suppress auxin-mediated primary root elongation in Arabidopsis. Wu Y, et al. New Phytol, 2022 Jan. PMID 34618941
    3. The Asparagine-Rich Protein NRP Facilitates the Degradation of the PP6-type Phosphatase FyPP3 to Promote ABA Response in Arabidopsis. Zhu T, et al. Mol Plant, 2018 Feb 5. PMID 29175650
    4. The asparagine-rich protein NRP interacts with the Verticillium effector PevD1 and regulates the subcellular localization of cryptochrome 2. Zhou R, et al. J Exp Bot, 2017 Jun 15. PMID 28633330
    5. Stress response proteins NRP1 and NRP2 are pro-survival factors that inhibit cell death during ER stress. Yang Y, et al. Plant Physiol, 2021 Nov 3. PMID 34618053, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Stress response proteins NRP1 and NRP2 are pro-survival factors that inhibit cell death during ER stress.
      Title: Stress response proteins NRP1 and NRP2 are pro-survival factors that inhibit cell death during ER stress.
    2. Verticillium dahliae PevD1 indirectly activates Arabidopsis CRY2 by antagonizing NRP functions. The promotion of CRY2-mediated flowering by a fungal effector outlines a novel pathway by which an external stimulus is recognized and transferred in changing a developmental program.
      Title: The asparagine-rich protein NRP interacts with the Verticillium effector PevD1 and regulates the subcellular localization of cryptochrome 2.
    3. Asparagine-rich proten (NRP)is involved in the signal transduction of the initial phase of general stress response in Arabidopsis thaliana. [NRP]
      Title: Investigations on N-rich protein (NRP) of Arabidopsis thaliana under different stress conditions.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_123570.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    involved_in regulation of programmed cell death IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of protein catabolic process in the vacuole IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to endoplasmic reticulum stress IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in response to salt IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    colocalizes_with endosome IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    DCD (Development and Cell Death) domain protein
    NP_568600.1
    • DCD (Development and Cell Death) domain protein; CONTAINS InterPro DOMAIN/s: Development/cell death domain (InterPro:IPR013989), Kelch related (InterPro:IPR013089); BEST Arabidopsis thaliana protein match is: DCD (Development and Cell Death) domain protein (TAIR:AT3G27090.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      16815310..16817346
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123570.4 → NP_568600.1  DCD (Development and Cell Death) domain protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568600.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8RXN8, Q9FHX9
      UniProtKB/TrEMBL
      A0A178UIL7, A0A7G2FGW5
      Conserved Domains (1) summary
      smart00767
      Location:214 → 345
      DCD; DCD is a plant specific domain in proteins involved in development and programmed cell death
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8RXN8.1

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