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    RAC10 RAC-like 10 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836408, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RAC10
    Official Full Name
    RAC-like 10
    Primary source
    TAIR:AT5G62880
    Locus tag
    AT5G62880
    See related
    Araport:AT5G62880
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA RAC-LIKE 10; ARAC10; ATRAC10; ATROP11; MQB2.180; MQB2_180; RAC-like 10; RHO-related protein from plants 11; RHO-RELATED PROTEIN FROM PLANTS 11; ROP11
    Summary
    A member of ROP GTPase gene family.
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    Genomic context

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    See RAC10 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (25236945..25239262)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene F-box associated ubiquitination effector family protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Xanthine/uracil permease family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ROP11 GTPase is a negative regulator of multiple ABA responses in Arabidopsis. Li Z, et al. J Integr Plant Biol, 2012 Mar. PMID 22233300
    2. Instability of the Arabidopsis mutant csn5a-2 caused by epigenetic modification of intronic T-DNA. Jia X, et al. Plant Sci, 2015 Sep. PMID 26259174
    3. A Rho-actin signaling pathway shapes cell wall boundaries in Arabidopsis xylem vessels. Sugiyama Y, et al. Nat Commun, 2019 Jan 28. PMID 30692538, Free PMC Article
    4. ROP11 GTPase negatively regulates ABA signaling by protecting ABI1 phosphatase activity from inhibition by the ABA receptor RCAR1/PYL9 in Arabidopsis. Li Z, et al. J Integr Plant Biol, 2012 Mar. PMID 22251383, Free PMC Article
    5. Cloning and characterization of rac-like cDNAs from Arabidopsis thaliana. Winge P, et al. Plant Mol Biol, 1997 Nov. PMID 9349271

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The model predicted that a positive feedback and slow diffusion of ROP11-ROPGEF4 complex were required to generate ROP-activated plasma membrane domains.
      Title: A Rho-based reaction-diffusion system governs cell wall patterning in metaxylem vessels.
    2. Data indicate that ROP11 GTPase (At5g62880) can be activated locally at the plasma membrane.
      Title: A Rho-actin signaling pathway shapes cell wall boundaries in Arabidopsis xylem vessels.
    3. ROP11 protects ABI1 phosphatase activity from inhibition by RCAR1/PYL9 and thus negatively regulates abscissic acid signaling.[ROP11]
      Title: ROP11 GTPase negatively regulates ABA signaling by protecting ABI1 phosphatase activity from inhibition by the ABA receptor RCAR1/PYL9 in Arabidopsis.
    4. ROP11 is a negative regulator of multiple abscissic acid responses in Arabidopsis.[ROP11]
      Title: ROP11 GTPase is a negative regulator of multiple ABA responses in Arabidopsis.
    5. ROPGEF1 and ROPGEF4 are specific regulators of ROP11 function in ABA-mediated stomatal closure. [ROP11]
      Title: ROPGEF1 and ROPGEF4 are functional regulators of ROP11 GTPase in ABA-mediated stomatal closure in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_125682.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTP binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein phosphatase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of abscisic acid-activated signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within plant-type cell wall organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of plant-type cell wall cellulose biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in secondary cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RAC-like 10
    NP_201093.1
    • RAC-like 10 (RAC10); FUNCTIONS IN: GTP binding; INVOLVED IN: protein transport, small GTPase mediated signal transduction; LOCATED IN: plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Ras small GTPase, Rab type (InterPro:IPR003579), Ras (InterPro:IPR013753), Ras small GTPase, Ras type (InterPro:IPR003577), Small GTPase, Rho type (InterPro:IPR003578); BEST Arabidopsis thaliana protein match is: RHO-related protein from plants 10 (TAIR:AT3G48040.1); Has 24116 Blast hits to 24088 proteins in 664 species: Archae - 8; Bacteria - 52; Metazoa - 12643; Fungi - 3430; Plants - 2696; Viruses - 20; Other Eukaryotes - 5267 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25236945..25239262
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001345564.1 → NP_001331034.1  RAC-like 10 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BCM4, A0A654FEQ4
      Conserved Domains (1) summary
      cd04133
      Location:8 → 166
      Rop_like; Rho-related protein from plants (Rop)-like

    2. NM_125682.5 → NP_201093.1  RAC-like 10 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201093.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82481
      UniProtKB/TrEMBL
      A0A178UC00, A0A384LM06, Q67XC6, Q683A3
      Conserved Domains (1) summary
      cd04133
      Location:8 → 180
      Rop_like; Rho-related protein from plants (Rop)-like
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O82481.1

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