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    AAP4 amino acid permease 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836505, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AAP4
    Official Full Name
    amino acid permease 4
    Primary source
    TAIR:AT5G63850
    Locus tag
    AT5G63850
    See related
    Araport:AT5G63850
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    amino acid permease 4; MGI19.6; MGI19_6
    Summary
    Amino acid transporter whose expression is downregulated by dehydration.
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    Genomic context

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    See AAP4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Sequence:
    Chromosome: 5; NC_003076.8 (25550937..25553656)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene HIT-type Zinc finger family protein Neighboring gene Glycosyl hydrolases family 31 protein Neighboring gene Regulator of chromosome condensation (RCC1) family protein Neighboring gene serine/threonine phosphatase 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Substrate specificity and expression profile of amino acid transporters (AAPs) in Arabidopsis. Fischer WN, et al. J Biol Chem, 1995 Jul 7. PMID 7608199
    2. Uncovering Arabidopsis membrane protein interactome enriched in transporters using mating-based split ubiquitin assays and classification models. Chen J, et al. Front Plant Sci, 2012. PMID 22737156, Free PMC Article
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_125780.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables acidic amino acid transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables amino acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables neutral L-amino acid transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables primary active transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within amino acid transport TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    amino acid permease 4
    NP_201190.1
    • amino acid permease 4 (AAP4); CONTAINS InterPro DOMAIN/s: Amino acid transporter, transmembrane (InterPro:IPR013057); BEST Arabidopsis thaliana protein match is: amino acid permease 2 (TAIR:AT5G09220.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25550937..25553656
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125780.3 → NP_201190.1  amino acid permease 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201190.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39135, Q8LFM7, Q8RWA8, Q9FN04
      UniProtKB/TrEMBL
      A0A178UDW1, A0A5S9YHG1
      Conserved Domains (1) summary
      pfam01490
      Location:19 → 454
      Aa_trans; Transmembrane amino acid transporter protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FN04.1

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