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    SDH1-1 succinate dehydrogenase 1-1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836809, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SDH1-1
    Official Full Name
    succinate dehydrogenase 1-1
    Primary source
    TAIR:AT5G66760
    Locus tag
    AT5G66760
    See related
    Araport:AT5G66760
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MSN2.16; MSN2_16; succinate dehydrogenase 1-1
    Summary
    One of two genes in Arabidopsis that encode a flavoprotein subunit of the mitochondrial succinate dehydrogenase complex.
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    Genomic context

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    See SDH1-1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    15
    Sequence:
    Chromosome: 5; NC_003076.8 (26653607..26657696)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene chromatin remodeling 1 Neighboring gene tRNA-Glu Neighboring gene ncRNA Neighboring gene GRAS family transcription factor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Salicylic Acid-Dependent Plant Stress Signaling via Mitochondrial Succinate Dehydrogenase. Belt K, et al. Plant Physiol, 2017 Apr. PMID 28209841, Free PMC Article
    2. A deficiency in the flavoprotein of Arabidopsis mitochondrial complex II results in elevated photosynthesis and better growth in nitrogen-limiting conditions. Fuentes D, et al. Plant Physiol, 2011 Nov. PMID 21921116, Free PMC Article
    3. The four subunits of mitochondrial respiratory complex II are encoded by multiple nuclear genes and targeted to mitochondria in Arabidopsis thaliana. Figueroa P, et al. Plant Mol Biol, 2002 Nov. PMID 12374303
    4. Mitochondrial cytochrome c oxidase and succinate dehydrogenase complexes contain plant specific subunits. Millar AH, et al. Plant Mol Biol, 2004 Sep. PMID 15604729
    5. Functional and composition differences between mitochondrial complex II in Arabidopsis and rice are correlated with the complex genetic history of the enzyme. Huang S, et al. Plant Mol Biol, 2010 Feb. PMID 19924544

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data sugggest that salicylic acid (SA) acts at or near the ubiquinone binding site of mitochondrial succinate dehydrogenase (SDH) to stimulate activity and contributes to plant stress signaling by increased rates of mitochondrial H2O2 production.
      Title: Salicylic Acid-Dependent Plant Stress Signaling via Mitochondrial Succinate Dehydrogenase.
    2. SDH1-1/sdh1-1 seedlings grew considerably better in nitrogen-limiting conditions.
      Title: A deficiency in the flavoprotein of Arabidopsis mitochondrial complex II results in elevated photosynthesis and better growth in nitrogen-limiting conditions.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_126074.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding HDA PubMed 
    enables cobalt ion binding HDA PubMed 
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables succinate dehydrogenase (quinone) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables succinate dehydrogenase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within mitochondrial electron transport, succinate to ubiquinone TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in tricarboxylic acid cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    NOT located_in Golgi apparatus RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type cell wall HDA PubMed 
    located_in plastid HDA PubMed 
    part_of respiratory chain complex II (succinate dehydrogenase) IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of respiratory chain complex II (succinate dehydrogenase) ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    succinate dehydrogenase 1-1
    NP_201477.1
    • succinate dehydrogenase 1-1 (SDH1-1); FUNCTIONS IN: cobalt ion binding, succinate dehydrogenase activity, ATP binding; INVOLVED IN: mitochondrial electron transport, succinate to ubiquinone; LOCATED IN: mitochondrial respiratory chain complex II, mitochondrion, cell wall; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Succinate dehydrogenase, flavoprotein subunit (InterPro:IPR011281), Fumarate reductase/succinate dehydrogenase, FAD-binding site (InterPro:IPR003952), Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (InterPro:IPR015939), Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal (InterPro:IPR003953), Succinate dehydrogenase/fumarate reductase, flavoprotein subunit (InterPro:IPR014006), Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal (InterPro:IPR004112); BEST Arabidopsis thaliana protein match is: succinate dehydrogenase 1-2 (TAIR:AT2G18450.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      26653607..26657696
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126074.3 → NP_201477.1  succinate dehydrogenase 1-1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201477.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82663
      UniProtKB/TrEMBL
      A0A178UAN3, A0A5S9YIF0, A0A7G2E9B3
      Conserved Domains (1) summary
      PLN00128
      Location:1 → 634
      PLN00128; Succinate dehydrogenase [ubiquinone] flavoprotein subunit
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O82663.1

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