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    PAB4 poly(A) binding protein 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816867, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PAB4
    Official Full Name
    poly(A) binding protein 4
    Primary source
    TAIR:AT2G23350
    Locus tag
    AT2G23350
    See related
    Araport:AT2G23350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    PABP4; poly(A) binding protein 4; POLY(A) BINDING PROTEIN 4; T20D16.2; T20D16_2
    Summary
    polyadenylate-binding protein, putative / PABP, putative.Member of the Class II family of PABP proteins. Highly and ubiquitously expressed.
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    Genomic context

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    See PAB4 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Sequence:
    Chromosome: 2; NC_003071.7 (9942915..9946347)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene DREB and EAR motif protein 3 Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene filament-like protein (DUF869) Neighboring gene cyclin delta-3 Neighboring gene SET domain-containing protein Neighboring gene acyl-CoA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ERD15--an attenuator of plant ABA responses and stomatal aperture. Aalto MK, et al. Plant Sci, 2012 Jan. PMID 22118612
    2. Interactome of the plant-specific ESCRT-III component AtVPS2.2 in Arabidopsis thaliana. Ibl V, et al. J Proteome Res, 2012 Jan 1. PMID 22010978, Free PMC Article
    3. Protein and metabolite composition of Arabidopsis stress granules. Kosmacz M, et al. New Phytol, 2019 May. PMID 30664249
    4. In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings. Reichel M, et al. Plant Cell, 2016 Oct. PMID 27729395, Free PMC Article
    5. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_127899.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables translation initiation factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in vacuole HDA PubMed 

    General protein information

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    Preferred Names
    poly(A) binding protein 4
    NP_179916.1
    • poly(A) binding protein 4 (PAB4); FUNCTIONS IN: RNA binding, translation initiation factor activity; INVOLVED IN: response to cadmium ion; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Polyadenylate-binding protein/Hyperplastic disc protein (InterPro:IPR002004), RNA recognition motif, RNP-1 (InterPro:IPR000504), Polyadenylate binding protein, human types 1, 2, 3, 4 (InterPro:IPR006515), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: poly(A) binding protein 2 (TAIR:AT4G34110.1); Has 520413 Blast hits to 486687 proteins in 21592 species: Archae - 10501; Bacteria - 294432; Metazoa - 110769; Fungi - 17969; Plants - 36260; Viruses - 34479; Other Eukaryotes - 16003 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      9942915..9946347
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127899.4 → NP_179916.1  poly(A) binding protein 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179916.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22173, Q9C5J0
      UniProtKB/TrEMBL
      A0A178VSF7, A0A5S9X0L1, A0A7G2EAE7
      Conserved Domains (1) summary
      TIGR01628
      Location:47 → 631
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22173.1

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