NEW
Try the new Transcript table
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001258374.3 → NP_001245303.1 epidermal growth factor receptor substrate 15-like 1 isoform 1
See identical proteins and their annotated locations for NP_001245303.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
AC008764, AC020917
- Consensus CDS
-
CCDS58654.1
- UniProtKB/TrEMBL
-
B4DME4
- Related
- ENSP00000393313.1, ENST00000455140.7
- Conserved Domains (3) summary
-
- smart00027
Location:121 → 214
- EH; Eps15 homology domain
- COG1196
Location:384 → 569
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00052
Location:19 → 85
- EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
-
NM_001258375.2 → NP_001245304.1 epidermal growth factor receptor substrate 15-like 1 isoform 3
See identical proteins and their annotated locations for NP_001245304.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) differs in the 3' UTR and lacks an exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AK024166, BC131590, BU075732
- Consensus CDS
-
CCDS58653.1
- UniProtKB/TrEMBL
-
M0R165
- Related
- ENSP00000440103.1, ENST00000535753.6
- Conserved Domains (3) summary
-
- smart00027
Location:121 → 214
- EH; Eps15 homology domain
- COG1196
Location:384 → 569
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00052
Location:19 → 85
- EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
-
NM_001258376.2 → NP_001245305.1 epidermal growth factor receptor substrate 15-like 1 isoform 4
See identical proteins and their annotated locations for NP_001245305.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) differs in the 3' UTR, compared to variant 1. The encoded isoform (4) is shorter and has a distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AC020917, AU121887, BC142716, CA446537
- Consensus CDS
-
CCDS59363.1
- UniProtKB/TrEMBL
-
A5PKY0
- Related
- ENSP00000472267.1, ENST00000597937.5
- Conserved Domains (3) summary
-
- smart00027
Location:121 → 214
- EH; Eps15 homology domain
- cd00052
Location:19 → 85
- EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
- cl25732
Location:385 → 569
- SMC_N; RecF/RecN/SMC N terminal domain
-
NM_021235.3 → NP_067058.1 epidermal growth factor receptor substrate 15-like 1 isoform 2
See identical proteins and their annotated locations for NP_067058.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AF110265, AU121887, BU075732
- Consensus CDS
-
CCDS32944.1
- UniProtKB/Swiss-Prot
- A2RRF3, A5PL29, B4DKA3, Q9UBC2
- UniProtKB/TrEMBL
-
B4DME4
- Related
- ENSP00000248070.5, ENST00000248070.10
- Conserved Domains (4) summary
-
- smart00027
Location:121 → 214
- EH; Eps15 homology domain
- cd00052
Location:131 → 196
- EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
- cd00176
Location:385 → 572
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam15619
Location:385 → 555
- Lebercilin; Ciliary protein causing Leber congenital amaurosis disease
RNA
-
NR_047665.2 RNA Sequence
Status: VALIDATED
- Description
- Transcript Variant: This variant (5) lacks an internal exon in the 3' region, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC008764, AC020917
-
NR_047666.1 RNA Sequence
Status: VALIDATED
- Source sequence(s)
-
AK297428, AU121887, BU075732, DC416977
- Related
-
ENST00000592031.5
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000019.10 Reference GRCh38.p14 Primary Assembly
- Range
-
16355247..16472012 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017027090.3 → XP_016882579.1 epidermal growth factor receptor substrate 15-like 1 isoform X5
- UniProtKB/TrEMBL
-
M0R165
- Conserved Domains (3) summary
-
- smart00027
Location:121 → 214
- EH; Eps15 homology domain
- COG1196
Location:385 → 569
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00052
Location:19 → 85
- EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
-
XM_017027091.3 → XP_016882580.1 epidermal growth factor receptor substrate 15-like 1 isoform X6
- UniProtKB/TrEMBL
-
M0R165
- Conserved Domains (3) summary
-
- smart00027
Location:121 → 214
- EH; Eps15 homology domain
- COG1196
Location:384 → 569
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00052
Location:19 → 85
- EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
-
XM_047439173.1 → XP_047295129.1 epidermal growth factor receptor substrate 15-like 1 isoform X3
- UniProtKB/TrEMBL
-
M0R165
-
XM_017027089.3 → XP_016882578.1 epidermal growth factor receptor substrate 15-like 1 isoform X2
- UniProtKB/TrEMBL
-
M0R165
-
XM_017027086.3 → XP_016882575.1 epidermal growth factor receptor substrate 15-like 1 isoform X1
- UniProtKB/TrEMBL
- A0AAQ5BI61, B4DME4
- Related
- ENSP00000519782.1, ENST00000714540.1
-
XM_047439174.1 → XP_047295130.1 epidermal growth factor receptor substrate 15-like 1 isoform X4
- UniProtKB/TrEMBL
-
B4DME4
-
XM_017027092.3 → XP_016882581.1 epidermal growth factor receptor substrate 15-like 1 isoform X7
- UniProtKB/TrEMBL
-
M0R165
Alternate T2T-CHM13v2.0
Genomic
-
NC_060943.1 Alternate T2T-CHM13v2.0
- Range
-
16490074..16606830 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054321640.1 → XP_054177615.1 epidermal growth factor receptor substrate 15-like 1 isoform X5
- UniProtKB/TrEMBL
-
M0R165
-
XM_054321641.1 → XP_054177616.1 epidermal growth factor receptor substrate 15-like 1 isoform X6
- UniProtKB/TrEMBL
-
M0R165
-
XM_054321638.1 → XP_054177613.1 epidermal growth factor receptor substrate 15-like 1 isoform X3
- UniProtKB/TrEMBL
-
M0R165
-
XM_054321637.1 → XP_054177612.1 epidermal growth factor receptor substrate 15-like 1 isoform X2
- UniProtKB/TrEMBL
-
M0R165
-
XM_054321636.1 → XP_054177611.1 epidermal growth factor receptor substrate 15-like 1 isoform X1
- UniProtKB/TrEMBL
- A0AAQ5BI61, B4DME4
-
XM_054321639.1 → XP_054177614.1 epidermal growth factor receptor substrate 15-like 1 isoform X4
- UniProtKB/TrEMBL
-
B4DME4
-
XM_054321642.1 → XP_054177617.1 epidermal growth factor receptor substrate 15-like 1 isoform X7
- UniProtKB/TrEMBL
-
M0R165