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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029465.2 RefSeqGene
- Range
-
5001..114630
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_459
mRNA and Protein(s)
-
NM_001320892.2 → NP_001307821.1 DNA (cytosine-5)-methyltransferase 3A isoform c
Status: REVIEWED
- Source sequence(s)
-
AC012074, AL543971, BC032392, BC043617
- Consensus CDS
-
CCDS46232.1
- UniProtKB/Swiss-Prot
-
Q9Y6K1
- Conserved Domains (1) summary
-
- PTZ00449
Location:4 → 82
- PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
-
NM_001320893.1 → NP_001307822.1 DNA (cytosine-5)-methyltransferase 3A isoform d
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) uses a downstream promoter compared to variants 1, 3, 4 and 7.
- Source sequence(s)
-
AB208833, AC012074, AF480163, AI376254
- UniProtKB/Swiss-Prot
-
Q9Y6K1
- UniProtKB/TrEMBL
-
Q59HC6
- Conserved Domains (4) summary
-
- cd05835
Location:138 → 224
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- COG0270
Location:480 → 643
- Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
- PRK07003
Location:30 → 130
- PRK07003; DNA polymerase III subunit gamma/tau
- cd11729
Location:335 → 462
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
-
NM_001375819.1 → NP_001362748.1 DNA (cytosine-5)-methyltransferase 3A isoform e
Status: REVIEWED
- Source sequence(s)
-
AC012074
- Consensus CDS
-
CCDS92718.1
- UniProtKB/TrEMBL
-
A0A0C4DG02
- Related
- ENSP00000384237.1, ENST00000402667.1
- Conserved Domains (3) summary
-
- cd05835
Location:67 → 153
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- cd11729
Location:264 → 391
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
- cl30459
Location:409 → 572
- Cyt_C5_DNA_methylase; Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group ...
-
NM_022552.5 → NP_072046.2 DNA (cytosine-5)-methyltransferase 3A isoform a
See identical proteins and their annotated locations for NP_072046.2
Status: REVIEWED
- Source sequence(s)
-
AC012074
- Consensus CDS
-
CCDS33157.1
- UniProtKB/Swiss-Prot
- E9PEB8, Q86TE8, Q86XF5, Q8IZV0, Q8WXU9, Q9Y6K1
- UniProtKB/TrEMBL
-
Q59HC6
- Related
- ENSP00000324375.5, ENST00000321117.10
- Conserved Domains (4) summary
-
- cd05835
Location:290 → 376
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- COG0270
Location:632 → 795
- Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
- cd11729
Location:487 → 614
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
- cl25756
Location:11 → 156
- BASP1; Brain acid soluble protein 1 (BASP1 protein)
-
NM_153759.3 → NP_715640.2 DNA (cytosine-5)-methyltransferase 3A isoform b
See identical proteins and their annotated locations for NP_715640.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses a downstream promoter compared to variants 1, 3, 4, and 7.
- Source sequence(s)
-
AF331856, AF480163, AI376254, BM470515
- Consensus CDS
-
CCDS1718.2
- UniProtKB/Swiss-Prot
-
Q9Y6K1
- Related
- ENSP00000370122.4, ENST00000380746.8
- Conserved Domains (3) summary
-
- cd05835
Location:101 → 187
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- COG0270
Location:443 → 606
- Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
- cd11729
Location:298 → 425
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
-
NM_175629.2 → NP_783328.1 DNA (cytosine-5)-methyltransferase 3A isoform a
See identical proteins and their annotated locations for NP_783328.1
Status: REVIEWED
- Source sequence(s)
-
AF331856, AI376254, BC032392
- Consensus CDS
-
CCDS33157.1
- UniProtKB/Swiss-Prot
- E9PEB8, Q86TE8, Q86XF5, Q8IZV0, Q8WXU9, Q9Y6K1
- UniProtKB/TrEMBL
-
Q59HC6
- Related
- ENSP00000264709.3, ENST00000264709.7
- Conserved Domains (4) summary
-
- cd05835
Location:290 → 376
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- COG0270
Location:632 → 795
- Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
- cd11729
Location:487 → 614
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
- cl25756
Location:11 → 156
- BASP1; Brain acid soluble protein 1 (BASP1 protein)
-
NM_175630.1 → NP_783329.1 DNA (cytosine-5)-methyltransferase 3A isoform c
See identical proteins and their annotated locations for NP_783329.1
Status: REVIEWED
- Source sequence(s)
-
BC032392
- Consensus CDS
-
CCDS46232.1
- UniProtKB/Swiss-Prot
-
Q9Y6K1
- Related
- ENSP00000384852.3, ENST00000406659.3
RNA
-
NR_135490.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AB208833, AC012074, AI376254
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000002.12 Reference GRCh38.p14 Primary Assembly
- Range
-
25227874..25342590 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_005264175.6 → XP_005264232.1 DNA (cytosine-5)-methyltransferase 3A isoform X1
See identical proteins and their annotated locations for XP_005264232.1
- UniProtKB/Swiss-Prot
- E9PEB8, Q86TE8, Q86XF5, Q8IZV0, Q8WXU9, Q9Y6K1
- UniProtKB/TrEMBL
-
Q59HC6
- Conserved Domains (4) summary
-
- cd05835
Location:290 → 376
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- COG0270
Location:632 → 795
- Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
- cd11729
Location:487 → 614
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
- cl25756
Location:11 → 156
- BASP1; Brain acid soluble protein 1 (BASP1 protein)
-
XM_017003526.2 → XP_016859015.1 DNA (cytosine-5)-methyltransferase 3A isoform X1
- UniProtKB/Swiss-Prot
- E9PEB8, Q86TE8, Q86XF5, Q8IZV0, Q8WXU9, Q9Y6K1
- UniProtKB/TrEMBL
-
Q59HC6
- Conserved Domains (4) summary
-
- cd05835
Location:290 → 376
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- COG0270
Location:632 → 795
- Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
- cd11729
Location:487 → 614
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
- cl25756
Location:11 → 156
- BASP1; Brain acid soluble protein 1 (BASP1 protein)
-
XM_011532662.3 → XP_011530964.1 DNA (cytosine-5)-methyltransferase 3A isoform X2
- UniProtKB/TrEMBL
-
Q59HC6
- Conserved Domains (3) summary
-
- cd05835
Location:241 → 327
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- COG0270
Location:583 → 746
- Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
- cd11729
Location:438 → 565
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
-
XM_047443592.1 → XP_047299548.1 DNA (cytosine-5)-methyltransferase 3A isoform X3
-
XM_047443594.1 → XP_047299550.1 DNA (cytosine-5)-methyltransferase 3A isoform X7
-
XM_011532667.4 → XP_011530969.1 DNA (cytosine-5)-methyltransferase 3A isoform X8
See identical proteins and their annotated locations for XP_011530969.1
- UniProtKB/TrEMBL
-
A0A0C4DG02
- Conserved Domains (3) summary
-
- cd05835
Location:67 → 153
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- cd11729
Location:264 → 391
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
- cl30459
Location:409 → 572
- Cyt_C5_DNA_methylase; Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group ...
-
XM_017003527.2 → XP_016859016.1 DNA (cytosine-5)-methyltransferase 3A isoform X8
- UniProtKB/TrEMBL
-
A0A0C4DG02
- Conserved Domains (3) summary
-
- cd05835
Location:67 → 153
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- cd11729
Location:264 → 391
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
- cl30459
Location:409 → 572
- Cyt_C5_DNA_methylase; Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group ...
-
XM_047443598.1 → XP_047299554.1 DNA (cytosine-5)-methyltransferase 3A isoform X8
- UniProtKB/TrEMBL
-
A0A0C4DG02
-
XM_011532666.3 → XP_011530968.1 DNA (cytosine-5)-methyltransferase 3A isoform X6
See identical proteins and their annotated locations for XP_011530968.1
- Conserved Domains (3) summary
-
- cd05835
Location:114 → 200
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- COG0270
Location:456 → 619
- Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
- cd11729
Location:311 → 438
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
-
XM_047443596.1 → XP_047299552.1 DNA (cytosine-5)-methyltransferase 3A isoform X8
- UniProtKB/TrEMBL
-
A0A0C4DG02
-
XM_047443597.1 → XP_047299553.1 DNA (cytosine-5)-methyltransferase 3A isoform X8
- UniProtKB/TrEMBL
-
A0A0C4DG02
-
XM_047443593.1 → XP_047299549.1 DNA (cytosine-5)-methyltransferase 3A isoform X4
- UniProtKB/TrEMBL
-
Q59HC6
-
XM_011532664.3 → XP_011530966.1 DNA (cytosine-5)-methyltransferase 3A isoform X5
See identical proteins and their annotated locations for XP_011530966.1
- UniProtKB/TrEMBL
- F8WE91, Q59HC6
- Related
- ENSP00000370132.3, ENST00000380756.7
- Conserved Domains (3) summary
-
- cd05835
Location:290 → 376
- Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
- COG0270
Location:632 → 781
- Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
- cd11729
Location:487 → 614
- ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)
-
XM_047443599.1 → XP_047299555.1 DNA (cytosine-5)-methyltransferase 3A isoform X9
Alternate T2T-CHM13v2.0
Genomic
-
NC_060926.1 Alternate T2T-CHM13v2.0
- Range
-
25263222..25377928 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054340901.1 → XP_054196876.1 DNA (cytosine-5)-methyltransferase 3A isoform X1
- UniProtKB/Swiss-Prot
- E9PEB8, Q86TE8, Q86XF5, Q8IZV0, Q8WXU9, Q9Y6K1
- UniProtKB/TrEMBL
-
Q59HC6
-
XM_054340900.1 → XP_054196875.1 DNA (cytosine-5)-methyltransferase 3A isoform X1
- UniProtKB/Swiss-Prot
- E9PEB8, Q86TE8, Q86XF5, Q8IZV0, Q8WXU9, Q9Y6K1
- UniProtKB/TrEMBL
-
Q59HC6
-
XM_054340902.1 → XP_054196877.1 DNA (cytosine-5)-methyltransferase 3A isoform X2
- UniProtKB/TrEMBL
-
Q59HC6
-
XM_054340903.1 → XP_054196878.1 DNA (cytosine-5)-methyltransferase 3A isoform X3
-
XM_054340909.1 → XP_054196884.1 DNA (cytosine-5)-methyltransferase 3A isoform X7
-
XM_054340910.1 → XP_054196885.1 DNA (cytosine-5)-methyltransferase 3A isoform X8
- UniProtKB/TrEMBL
-
A0A0C4DG02
-
XM_054340913.1 → XP_054196888.1 DNA (cytosine-5)-methyltransferase 3A isoform X8
- UniProtKB/TrEMBL
-
A0A0C4DG02
-
XM_054340908.1 → XP_054196883.1 DNA (cytosine-5)-methyltransferase 3A isoform X6
-
XM_054340911.1 → XP_054196886.1 DNA (cytosine-5)-methyltransferase 3A isoform X8
- UniProtKB/TrEMBL
-
A0A0C4DG02
-
XM_054340912.1 → XP_054196887.1 DNA (cytosine-5)-methyltransferase 3A isoform X8
- UniProtKB/TrEMBL
-
A0A0C4DG02
-
XM_054340907.1 → XP_054196882.1 DNA (cytosine-5)-methyltransferase 3A isoform X11
-
XM_054340906.1 → XP_054196881.1 DNA (cytosine-5)-methyltransferase 3A isoform X10
-
XM_054340904.1 → XP_054196879.1 DNA (cytosine-5)-methyltransferase 3A isoform X4
- UniProtKB/TrEMBL
-
Q59HC6
-
XM_054340915.1 → XP_054196890.1 DNA (cytosine-5)-methyltransferase 3A isoform X5
- UniProtKB/TrEMBL
- F8WE91, Q59HC6
-
XM_054340905.1 → XP_054196880.1 DNA (cytosine-5)-methyltransferase 3A isoform X5
- UniProtKB/TrEMBL
- F8WE91, Q59HC6
-
XM_054340914.1 → XP_054196889.1 DNA (cytosine-5)-methyltransferase 3A isoform X9