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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_012567.1 RefSeqGene
- Range
-
4987..36022
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001271815.2 → NP_001258744.1 NADPH oxidase 1 isoform 3
See identical proteins and their annotated locations for NP_001258744.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an in-frame 5' coding exon, compared to variant 1 (NOH-1L). The resulting isoform (3) has the same N- and C-termini but is shorter, compared to isoform 1.
- Source sequence(s)
-
AF127763, AF166327, AI285296, AK292201, BX956931, DQ424904, Z83819
- Consensus CDS
-
CCDS65298.1
- UniProtKB/TrEMBL
- A6NGA6, Q1ZYL4
- Related
- ENSP00000362051.4, ENST00000372960.8
- Conserved Domains (2) summary
-
- cd06186
Location:260 → 527
- NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
- pfam01794
Location:48 → 176
- Ferric_reduct; Ferric reductase like transmembrane component
-
NM_007052.5 → NP_008983.2 NADPH oxidase 1 isoform 1
See identical proteins and their annotated locations for NP_008983.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1, alternately referred to as NOH-1L per PMID: 10615049) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AF127763, AF166327, BX956931, Z83819
- Consensus CDS
-
CCDS14474.1
- UniProtKB/Swiss-Prot
- A8K836, O95691, Q2PP02, Q9Y5S8
- UniProtKB/TrEMBL
-
Q1ZYL4
- Related
- ENSP00000362057.3, ENST00000372966.8
- Conserved Domains (2) summary
-
- cd06186
Location:297 → 564
- NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
- pfam01794
Location:66 → 213
- Ferric_reduct; Ferric reductase like transmembrane component
-
NM_013955.3 → NP_039249.1 NADPH oxidase 1 isoform 2
See identical proteins and their annotated locations for NP_039249.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2, alternately referred to as NOH-1Lv per PMID: 10615049) lacks an alternate in-frame coding exon, compared to variant 1 (NOH-1L). The resulting isoform (2) has the same N- and C-termini but is shorter, compared to isoform 1.
- Source sequence(s)
-
AF127763, AF166328, BX956931, Z83819
- Consensus CDS
-
CCDS14475.1
- UniProtKB/TrEMBL
-
Q8TCT3
- Related
- ENSP00000217885.5, ENST00000217885.5
- Conserved Domains (2) summary
-
- cd06186
Location:297 → 515
- NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
- pfam01794
Location:66 → 213
- Ferric_reduct; Ferric reductase like transmembrane component
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000023.11 Reference GRCh38.p14 Primary Assembly
- Range
-
100843324..100874359 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017029407.3 → XP_016884896.1 NADPH oxidase 1 isoform X1
- UniProtKB/TrEMBL
-
Q1ZYL4
Alternate T2T-CHM13v2.0
Genomic
-
NC_060947.1 Alternate T2T-CHM13v2.0
- Range
-
99285862..99317015 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054326825.1 → XP_054182800.1 NADPH oxidase 1 isoform X1
- UniProtKB/TrEMBL
-
Q1ZYL4
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_013954.1: Suppressed sequence
- Description
- NM_013954.1: This RefSeq was permanently suppressed because the submitters of the transcript data determined that this was not a biologically valid sequence.