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    Ubiquitin C-terminal hydrolases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828330, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Ubiquitin C-terminal hydrolases superfamily protein
    Primary source
    TAIR:AT4G22350
    Locus tag
    AT4G22350
    See related
    Araport:AT4G22350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T10I14.180; T10I14_180
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    10
    Sequence:
    Chromosome: 4; NC_003075.7 (11803768..11807417, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene microRNA ath-MIR8176 precursor Neighboring gene Alkaline phytoceramidase (aPHC) Neighboring gene cytidinediphosphate diacylglycerol synthase 2 Neighboring gene SWIB complex BAF60b domain-containing protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Ribosomal protein L7Ae/L30e/S12e/Gadd45 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. Ito J, et al. J Proteome Res, 2011 Apr 1. PMID 21166475
    2. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001203870.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in spliceosomal complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Ubiquitin C-terminal hydrolases superfamily protein
    NP_001190799.1
    • Ubiquitin C-terminal hydrolases superfamily protein; FUNCTIONS IN: ubiquitin thiolesterase activity, zinc ion binding; INVOLVED IN: ubiquitin-dependent protein catabolic process; EXPRESSED IN: male gametophyte, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Zinc finger, UBP-type (InterPro:IPR001607), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 (InterPro:IPR001394); BEST Arabidopsis thaliana protein match is: Ubiquitin C-terminal hydrolases superfamily protein (TAIR:AT4G22285.1).
    NP_193966.2
    • Ubiquitin C-terminal hydrolases superfamily protein; FUNCTIONS IN: ubiquitin thiolesterase activity, zinc ion binding; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: intracellular; EXPRESSED IN: male gametophyte, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), Zinc finger, UBP-type (InterPro:IPR001607), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 (InterPro:IPR001394); BEST Arabidopsis thaliana protein match is: Ubiquitin C-terminal hydrolases superfamily protein (TAIR:AT4G22285.1); Has 3525 Blast hits to 3024 proteins in 211 species: Archae - 0; Bacteria - 0; Metazoa - 2011; Fungi - 590; Plants - 433; Viruses - 0; Other Eukaryotes - 491 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      11803768..11807417 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118361.4 → NP_193966.2  Ubiquitin C-terminal hydrolases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193966.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2F036, Q8W0Z4
      Conserved Domains (2) summary
      cd02669
      Location:81 → 506
      Peptidase_C19M; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      pfam00443
      Location:200 → 505
      UCH; Ubiquitin carboxyl-terminal hydrolase

    2. NM_001341537.1 → NP_001328531.1  Ubiquitin C-terminal hydrolases superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UVD9, A0A1P8B4X8

    3. NM_001341536.1 → NP_001328532.1  Ubiquitin C-terminal hydrolases superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UVD9, A0A1P8B4X8

    4. NM_001203870.2 → NP_001190799.1  Ubiquitin C-terminal hydrolases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190799.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9XUR8, A0A654FRT8, F4JL64
      Conserved Domains (2) summary
      cd02669
      Location:110 → 535
      Peptidase_C19M; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      pfam00443
      Location:229 → 534
      UCH; Ubiquitin carboxyl-terminal hydrolase
    Nucleotide Protein
    Heading Accession and Version

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