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    UGE2 UDP-D-glucose/UDP-D-galactose 4-epimerase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828492, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UGE2
    Official Full Name
    UDP-D-glucose/UDP-D-galactose 4-epimerase 2
    Primary source
    TAIR:AT4G23920
    Locus tag
    AT4G23920
    See related
    Araport:AT4G23920
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATUGE2; T32A16.90; T32A16_90; UDP-D-glucose/UDP-D-galactose 4-epimerase 2; UDP-GLC 4-EPIMERASE 2
    Summary
    Encodes a protein with UDP-D-glucose 4-epimerase activity. Involved in growth and cell wall carbohydrate biosynthesis.
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    Genomic context

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    See UGE2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    9
    Sequence:
    Chromosome: 4; NC_003075.7 (12431097..12433912)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene tRNA-Ala Neighboring gene Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family Neighboring gene FtsH extracellular protease family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. UDP-glucose 4-epimerase isoforms UGE2 and UGE4 cooperate in providing UDP-galactose for cell wall biosynthesis and growth of Arabidopsis thaliana. Rösti J, et al. Plant Cell, 2007 May. PMID 17496119, Free PMC Article
    2. Distinct properties of the five UDP-D-glucose/UDP-D-galactose 4-epimerase isoforms of Arabidopsis thaliana. Barber C, et al. J Biol Chem, 2006 Jun 23. PMID 16644739
    3. Identification of Open Stomata1-Interacting Proteins Reveals Interactions with Sucrose Non-fermenting1-Related Protein Kinases2 and with Type 2A Protein Phosphatases That Function in Abscisic Acid Responses. Waadt R, et al. Plant Physiol, 2015 Sep. PMID 26175513, Free PMC Article
    4. Identification of multiple salicylic acid-binding proteins using two high throughput screens. Manohar M, et al. Front Plant Sci, 2014. PMID 25628632, Free PMC Article
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. UGE2 and UGE4 influence growth and cell wall carbohydrate biosynthesis throughout the plant, UGE3 is specialized for pollen development, and UGE1 and UGE5 might act in stress situations.
      Title: UDP-glucose 4-epimerase isoforms UGE2 and UGE4 cooperate in providing UDP-galactose for cell wall biosynthesis and growth of Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_118524.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables UDP-glucose 4-epimerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables UDP-glucose 4-epimerase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables protein dimerization activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables salicylic acid binding HDA PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell wall biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in galactose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    UDP-D-glucose/UDP-D-galactose 4-epimerase 2
    NP_194123.1
    • UDP-D-glucose/UDP-D-galactose 4-epimerase 2 (UGE2); CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040), UDP-glucose 4-epimerase (InterPro:IPR005886); BEST Arabidopsis thaliana protein match is: UDP-D-glucose/UDP-D-galactose 4-epimerase 5 (TAIR:AT4G10960.1); Has 45788 Blast hits to 45762 proteins in 3004 species: Archae - 838; Bacteria - 27545; Metazoa - 690; Fungi - 619; Plants - 1224; Viruses - 37; Other Eukaryotes - 14835 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      12431097..12433912
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118524.3 → NP_194123.1  UDP-D-glucose/UDP-D-galactose 4-epimerase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194123.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q541V9, Q8LFW1, Q9T0A7
      UniProtKB/TrEMBL
      A0A178V4G0, A0A5S9XW54
      Conserved Domains (2) summary
      PLN02240
      Location:1 → 338
      PLN02240; UDP-glucose 4-epimerase
      TIGR01179
      Location:5 → 337
      galE; UDP-glucose-4-epimerase GalE
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9T0A7.1

    Gene LinkOut

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