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    BT1 BTB and TAZ domain protein 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836437, updated on 18-Sep-2024

    Summary

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    Official Symbol
    BT1
    Official Full Name
    BTB and TAZ domain protein 1
    Primary source
    TAIR:AT5G63160
    Locus tag
    AT5G63160
    See related
    Araport:AT5G63160
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    BTB and TAZ domain protein 1; MDC12.13; MDC12_13
    Summary
    BTB and TAZ domain protein. Short-lived nuclear-cytoplasmic protein targeted for degradation by the 26S proteosome pathway. Acts redundantly with BT2 and BT3 during female gametophyte development.
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    Genomic context

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    See BT1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (25333172..25335570, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene tRNA-Thr Neighboring gene uncharacterized protein Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene Pectin lyase-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Direct transcriptional activation of BT genes by NLP transcription factors is a key component of the nitrate response in Arabidopsis. Sato T, et al. Biochem Biophys Res Commun, 2017 Jan 29. PMID 28025145
    2. Members of BTB Gene Family of Scaffold Proteins Suppress Nitrate Uptake and Nitrogen Use Efficiency. Araus V, et al. Plant Physiol, 2016 Jun. PMID 27208309, Free PMC Article
    3. BTB and TAZ domain scaffold proteins perform a crucial function in Arabidopsis development. Robert HS, et al. Plant J, 2009 Apr. PMID 19054356
    4. The transactivation domain within cysteine/histidine-rich region 1 of CBP comprises two novel zinc-binding modules. Newton AL, et al. J Biol Chem, 2000 May 19. PMID 10748221
    5. A novel family of Ca2+/calmodulin-binding proteins involved in transcriptional regulation: interaction with fsh/Ring3 class transcription activators. Du L, et al. Plant Mol Biol, 2004 Mar. PMID 15316289

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. direct activation of BT1 and BT2 by NLP transcriptional activators is a key component of the molecular mechanism underlying the nitrate response in Arabidopsis
      Title: Direct transcriptional activation of BT genes by NLP transcription factors is a key component of the nitrate response in Arabidopsis.
    2. Members of BTB Gene Family of Scaffold Proteins act as conserved negative regulators of nitrate uptake genes and nitrogen use efficiency in plants
      Title: Members of BTB Gene Family of Scaffold Proteins Suppress Nitrate Uptake and Nitrogen Use Efficiency.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001345580.1
    NM_001345581.1
    NM_125711.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calmodulin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo sac development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to auxin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to hydrogen peroxide IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to salicylic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    BTB and TAZ domain protein 1
    NP_201121.1
    • BTB and TAZ domain protein 1 (BT1); CONTAINS InterPro DOMAIN/s: BTB/POZ (InterPro:IPR013069), Zinc finger, TAZ-type (InterPro:IPR000197), BTB/POZ fold (InterPro:IPR011333), Kelch related (InterPro:IPR013089), BTB/POZ-like (InterPro:IPR000210); BEST Arabidopsis thaliana protein match is: BTB and TAZ domain protein 2 (TAIR:AT3G48360.1); Has 1462 Blast hits to 1460 proteins in 105 species: Archae - 0; Bacteria - 0; Metazoa - 839; Fungi - 0; Plants - 555; Viruses - 0; Other Eukaryotes - 68 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25333172..25335570 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125711.5 → NP_201121.1  BTB and TAZ domain protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201121.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FMK7
      UniProtKB/TrEMBL
      A0A5S9YH35, A0A654GDL4
      Conserved Domains (4) summary
      smart00225
      Location:26 → 122
      BTB; Broad-Complex, Tramtrack and Bric a brac
      cd14734
      Location:128 → 190
      SPOP_C; BACK-like Domain C-terminal to BTB in speckle-type POZ protein (SPOP) and similar proteins
      pfam02135
      Location:238 → 300
      zf-TAZ; TAZ zinc finger
      cl02518
      Location:25 → 122
      BTB; BTB/POZ domain

    2. NM_001345580.1 → NP_001331645.1  BTB and TAZ domain protein 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UB75, A0A1P8BEH5

    3. NM_001345581.1 → NP_001331644.1  BTB and TAZ domain protein 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BEI0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FMK7.1

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