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    LAS1 lanosterol synthase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823649, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LAS1
    Official Full Name
    lanosterol synthase 1
    Primary source
    TAIR:AT3G45130
    Locus tag
    AT3G45130
    See related
    Araport:AT3G45130
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    lanosterol synthase 1
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    Genomic context

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    See LAS1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    19
    Sequence:
    Chromosome: 3; NC_003074.8 (16512170..16517781, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lanosterol synthase in dicotyledonous plants. Suzuki M, et al. Plant Cell Physiol, 2006 May. PMID 16531458
    2. Lanosterol biosynthesis in plants. Kolesnikova MD, et al. Arch Biochem Biophys, 2006 Mar 1. PMID 16445886
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_001339196.1
    NM_001339197.1
    NM_114382.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables lanosterol synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in triterpenoid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in lipid droplet IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    lanosterol synthase 1
    NP_190099.3
    • lanosterol synthase 1 (LAS1); CONTAINS InterPro DOMAIN/s: Terpene synthase, conserved site (InterPro:IPR002365), Terpenoid cylases/protein prenyltransferase alpha-alpha toroid (InterPro:IPR008930), Squalene cyclase (InterPro:IPR018333), Prenyltransferase/squalene oxidase (InterPro:IPR001330); BEST Arabidopsis thaliana protein match is: cycloartenol synthase 1 (TAIR:AT2G07050.1); Has 2160 Blast hits to 1916 proteins in 566 species: Archae - 4; Bacteria - 1015; Metazoa - 82; Fungi - 243; Plants - 610; Viruses - 0; Other Eukaryotes - 206 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      16512170..16517781 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001339194.1 → NP_001327790.1  lanosterol synthase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LTE4, A0A7G2EU13

    2. NM_001339195.1 → NP_001327789.1  lanosterol synthase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LTE4, A0A7G2EU13

    3. NM_114382.5 → NP_190099.3  lanosterol synthase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190099.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1I9LTE2, Q1G1A4, Q9M1U6
      UniProtKB/TrEMBL
      A0A5S9XJK9, A0A654FE86, A0A7G2EU13
      Conserved Domains (1) summary
      PLN03012
      Location:1 → 751
      PLN03012; Camelliol C synthase

    4. NM_001339196.1 → NP_001327788.1  lanosterol synthase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1I9LTE2, Q1G1A4, Q9M1U6
      UniProtKB/TrEMBL
      A0A5S9XJK9, A0A654FE86, A0A7G2EU13
      Conserved Domains (1) summary
      PLN03012
      Location:1 → 751
      PLN03012; Camelliol C synthase

    5. NM_001339197.1 → NP_001327787.1  lanosterol synthase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1I9LTE2, Q1G1A4, Q9M1U6
      UniProtKB/TrEMBL
      A0A5S9XJK9, A0A654FE86, A0A7G2EU13
      Conserved Domains (1) summary
      PLN03012
      Location:1 → 751
      PLN03012; Camelliol C synthase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1G1A4.1

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