U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    AAE18 acyl-activating enzyme 18 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841977, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    AAE18
    Official Full Name
    acyl-activating enzyme 18
    Primary source
    TAIR:AT1G55320
    Locus tag
    AT1G55320
    See related
    Araport:AT1G55320
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    acyl-activating enzyme 18; F7A10.14; F7A10_14
    Summary
    Encodes a protein with similarity to acyl activating enzymes. AAE18 is localized to the peroxisome where it may be involved in metabolism of auxin precursors to active auxins.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See AAE18 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    14
    Sequence:
    Chromosome: 1; NC_003070.9 (20633096..20636892)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene TBP-associated factor 7 Neighboring gene SC35-like splicing factor 33 Neighboring gene RNA polymerase II transcription mediator Neighboring gene uncharacterized protein Neighboring gene arabinogalactan protein 21

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Identification of two Arabidopsis genes encoding a peroxisomal oxidoreductase-like protein and an acyl-CoA synthetase-like protein that are required for responses to pro-auxins. Wiszniewski AA, et al. Plant Mol Biol, 2009 Mar. PMID 19043666
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. An updated model for peroxisomal pro-auxin metabolism in Arabidopsis that includes SDRa and AAE18 is presented. AAE18 is capable of activating 2,4-dichlorophenoxybutyric acid (2,4-DB). [AAE18]
      Title: Identification of two Arabidopsis genes encoding a peroxisomal oxidoreductase-like protein and an acyl-CoA synthetase-like protein that are required for responses to pro-auxins.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Homology

    NM_001084254.1
    NM_104408.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within auxin metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    acyl-activating enzyme 18
    NP_001077723.1
    • acyl-activating enzyme 18 (AAE18); FUNCTIONS IN: catalytic activity, ligase activity; INVOLVED IN: metabolic process, auxin metabolic process; LOCATED IN: peroxisome; EXPRESSED IN: guard cell; CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: acyl-activating enzyme 17 (TAIR:AT5G23050.1); Has 26488 Blast hits to 26111 proteins in 2320 species: Archae - 743; Bacteria - 16022; Metazoa - 855; Fungi - 842; Plants - 335; Viruses - 0; Other Eukaryotes - 7691 (source: NCBI BLink).
    NP_175929.3
    • acyl-activating enzyme 18 (AAE18); FUNCTIONS IN: catalytic activity, ligase activity; INVOLVED IN: metabolic process, auxin metabolic process; LOCATED IN: peroxisome; EXPRESSED IN: guard cell; CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: acyl-activating enzyme 17 (TAIR:AT5G23050.1); Has 28626 Blast hits to 28179 proteins in 2353 species: Archae - 768; Bacteria - 16970; Metazoa - 908; Fungi - 873; Plants - 384; Viruses - 0; Other Eukaryotes - 8723 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      20633096..20636892
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104408.5 → NP_175929.3  acyl-activating enzyme 18 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175929.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4I094, Q84P17, Q8GZ95, Q9C8A3
      UniProtKB/TrEMBL
      A0A178WMT3, A0A5S9WPV1
      Conserved Domains (1) summary
      PLN03052
      Location:1 → 727
      PLN03052; acetate--CoA ligase; Provisional

    2. NM_001084254.1 → NP_001077723.1  acyl-activating enzyme 18 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077723.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84P17
      Conserved Domains (2) summary
      PLN03051
      Location:21 → 511
      PLN03051; acyl-activating enzyme; Provisional
      cl17068
      Location:12 → 498
      AFD_class_I; Adenylate forming domain, Class I superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84P17.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools