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    ATG8F Ubiquitin-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827351, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATG8F
    Official Full Name
    Ubiquitin-like superfamily protein
    Primary source
    TAIR:AT4G16520
    Locus tag
    AT4G16520
    See related
    Araport:AT4G16520
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    autophagy 8f; DL4285C; FCAALL.383
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    Genomic context

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    See ATG8F in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Sequence:
    Chromosome: 4; NC_003075.7 (9306339..9308538, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Cystatin/monellin superfamily protein Neighboring gene YbaK/aminoacyl-tRNA synthetase-associated domain-containing protein Neighboring gene root meristem growth factor Neighboring gene uncharacterized protein Neighboring gene leukocyte receptor cluster-like protein Neighboring gene Heat shock protein HSP20/alpha crystallin family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An autophagy-associated Atg8 protein is involved in the responses of Arabidopsis seedlings to hormonal controls and abiotic stresses. Slavikova S, et al. J Exp Bot, 2008. PMID 18836138, Free PMC Article
    2. Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7. Yamaguchi M, et al. Nat Struct Mol Biol, 2012 Dec. PMID 23142983
    3. The phosphatidylinositol 3-phosphate effector FYVE3 regulates FYVE2-dependent autophagy in Arabidopsis thaliana. Kim JH, et al. Front Plant Sci, 2023. PMID 37008475, Free PMC Article
    4. Overexpression of ATG8 in Arabidopsis Stimulates Autophagic Activity and Increases Nitrogen Remobilization Efficiency and Grain Filling. Chen Q, et al. Plant Cell Physiol, 2019 Feb 1. PMID 30407574
    5. A BAR-domain protein SH3P2, which binds to phosphatidylinositol 3-phosphate and ATG8, regulates autophagosome formation in Arabidopsis. Zhuang X, et al. Plant Cell, 2013 Nov. PMID 24249832, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. study shows that the overexpression of ATG8 genes provides beneficial effects on N management at the whole-plant level without affecting yield or plant biomass. [ATG8]
      Title: Overexpression of ATG8 in Arabidopsis Stimulates Autophagic Activity and Increases Nitrogen Remobilization Efficiency and Grain Filling.
    2. Expression of the AtAtg8 fusion construct renders the plants more sensitive to a mild salt stress and to a lesser extent to a mild osmotic stress.
      Title: An autophagy-associated Atg8 protein is involved in the responses of Arabidopsis seedlings to hormonal controls and abiotic stresses.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001341108.1
    NM_117751.4
    NM_179064.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in autophagosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Ubiquitin-like superfamily protein
    NP_567504.1
    • autophagy 8f (ATG8F); CONTAINS InterPro DOMAIN/s: Light chain 3 (LC3) (InterPro:IPR004241); BEST Arabidopsis thaliana protein match is: Ubiquitin-like superfamily protein (TAIR:AT3G60640.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_849395.1
    • autophagy 8f (ATG8F); CONTAINS InterPro DOMAIN/s: Light chain 3 (LC3) (InterPro:IPR004241); BEST Arabidopsis thaliana protein match is: Ubiquitin-like superfamily protein (TAIR:AT3G60640.1); Has 1518 Blast hits to 1516 proteins in 273 species: Archae - 0; Bacteria - 0; Metazoa - 724; Fungi - 178; Plants - 302; Viruses - 3; Other Eukaryotes - 311 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      9306339..9308538 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117751.4 → NP_567504.1  Ubiquitin-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567504.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23496, Q8VYK7
      Conserved Domains (1) summary
      cd16128
      Location:12 → 114
      Ubl_ATG8; ubiquitin-like (Ubl) domain found in Saccharomyces cerevisiae Atg8p and related proteins; sub-family of the autophagy-related 8 (ATG8) family

    2. NM_001341108.1 → NP_001329226.1  Ubiquitin-like superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B738

    3. NM_179064.2 → NP_849395.1  Ubiquitin-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849395.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23496, Q8VYK7
      Conserved Domains (1) summary
      cd16128
      Location:12 → 114
      Ubl_ATG8; ubiquitin-like (Ubl) domain found in Saccharomyces cerevisiae Atg8p and related proteins; sub-family of the autophagy-related 8 (ATG8) family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VYK7.1

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