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    PHL1 Homeodomain-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 833026, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PHL1
    Official Full Name
    Homeodomain-like superfamily protein
    Primary source
    TAIR:AT5G29000
    Locus tag
    AT5G29000
    See related
    Araport:AT5G29000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F3F24.100; F3F24_100; PHR1-like 1
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    Genomic context

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    See PHL1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (11021980..11024978, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene miscRNA Neighboring gene pseudo Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PHOSPHATE RESPONSE 1 family members act distinctly to regulate transcriptional responses to phosphate starvation. Wang Z, et al. Plant Physiol, 2023 Feb 12. PMID 36417239, Free PMC Article
    2. A central regulatory system largely controls transcriptional activation and repression responses to phosphate starvation in Arabidopsis. Bustos R, et al. PLoS Genet, 2010 Sep 9. PMID 20838596, Free PMC Article
    3. A complex tissue-specific interplay between the Arabidopsis transcription factors AtMYB68, AtHB23, and AtPHL1 modulates primary and lateral root development and adaptation to salinity. Spies FP, et al. Plant J, 2023 Aug. PMID 37165773
    4. Proline Accumulation Is Regulated by Transcription Factors Associated with Phosphate Starvation. Aleksza D, et al. Plant Physiol, 2017 Sep. PMID 28765275, Free PMC Article
    5. Molecular mechanism of phosphorous signaling inducing anthocyanin accumulation in Arabidopsis. Li H, et al. Plant Physiol Biochem, 2023 Mar. PMID 36706691

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PHOSPHATE RESPONSE 1 family members act distinctly to regulate transcriptional responses to phosphate starvation.
      Title: PHOSPHATE RESPONSE 1 family members act distinctly to regulate transcriptional responses to phosphate starvation.
    2. The results reveal a previously unknown link between Pro metabolism and phosphate nutrition and show that Pro biosynthesis is target of cross talk between Abscisic Acid (ABA) signaling and regulation of phosphate homeostasis through PHR1- and PHL1-mediated transcriptional activation of the P5CS1 gene.
      Title: Proline Accumulation Is Regulated by Transcription Factors Associated with Phosphate Starvation.
    3. PHR1 and PHL1 are partially redundant transcription factors acting as central integrators of phosphate starvation responses.[PHL1]
      Title: A central regulatory system largely controls transcriptional activation and repression responses to phosphate starvation in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    NM_001085160.2
    NM_001125827.1
    NM_122784.5
    NM_180759.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Homeodomain-like superfamily protein
    NP_001078629.1
    • Homeodomain-like superfamily protein; FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: nucleus, chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Myb, DNA-binding (InterPro:IPR014778), Homeodomain-like (InterPro:IPR009057), Homeodomain-related (InterPro:IPR012287), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Myb-like DNA-binding domain, SHAQKYF class (InterPro:IPR006447); BEST Arabidopsis thaliana protein match is: Homeodomain-like superfamily protein (TAIR:AT3G04450.2); Has 1716 Blast hits to 1701 proteins in 83 species: Archae - 0; Bacteria - 6; Metazoa - 10; Fungi - 10; Plants - 1661; Viruses - 0; Other Eukaryotes - 29 (source: NCBI BLink).
    NP_001119299.1
    • Homeodomain-like superfamily protein; FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), Myb-like DNA-binding domain, SHAQKYF class (InterPro:IPR006447), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: Homeodomain-like superfamily protein (TAIR:AT3G04450.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_568512.3
    • Homeodomain-like superfamily protein; FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Myb-like DNA-binding domain, SHAQKYF class (InterPro:IPR006447), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: Homeodomain-like superfamily protein (TAIR:AT3G04450.1); Has 1716 Blast hits to 1701 proteins in 83 species: Archae - 0; Bacteria - 6; Metazoa - 10; Fungi - 10; Plants - 1661; Viruses - 0; Other Eukaryotes - 29 (source: NCBI BLink).
    NP_851090.1
    • Homeodomain-like superfamily protein; FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: nucleus, chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Myb, DNA-binding (InterPro:IPR014778), Homeodomain-like (InterPro:IPR009057), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb-like DNA-binding domain, SHAQKYF class (InterPro:IPR006447); BEST Arabidopsis thaliana protein match is: Homeodomain-like superfamily protein (TAIR:AT3G04450.2); Has 1716 Blast hits to 1701 proteins in 83 species: Archae - 0; Bacteria - 6; Metazoa - 10; Fungi - 10; Plants - 1661; Viruses - 0; Other Eukaryotes - 29 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      11021980..11024978 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180759.4 → NP_851090.1  Homeodomain-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851090.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178ULG0, A0A7G2FB41
      Conserved Domains (2) summary
      TIGR01557
      Location:188 → 242
      myb_SHAQKYF; myb-like DNA-binding domain, SHAQKYF class
      pfam14379
      Location:277 → 323
      Myb_CC_LHEQLE; MYB-CC type transfactor, LHEQLE motif

    2. NM_122784.5 → NP_568512.3  Homeodomain-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568512.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H6E5, F4KBG7, Q8GUN5, Q8LEY3
      UniProtKB/TrEMBL
      A0A178ULC5, A0A5S9Y810
      Conserved Domains (2) summary
      TIGR01557
      Location:231 → 285
      myb_SHAQKYF; myb-like DNA-binding domain, SHAQKYF class
      pfam14379
      Location:320 → 366
      Myb_CC_LHEQLE; MYB-CC type transfactor, LHEQLE motif

    3. NM_001085160.2 → NP_001078629.1  Homeodomain-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078629.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178ULG0, A0A7G2FB41
      Conserved Domains (2) summary
      TIGR01557
      Location:188 → 242
      myb_SHAQKYF; myb-like DNA-binding domain, SHAQKYF class
      pfam14379
      Location:277 → 323
      Myb_CC_LHEQLE; MYB-CC type transfactor, LHEQLE motif

    4. NM_001125827.1 → NP_001119299.1  Homeodomain-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001119299.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GUN5
      Conserved Domains (1) summary
      TIGR01557
      Location:231 → 285
      myb_SHAQKYF; myb-like DNA-binding domain, SHAQKYF class
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8GUN5.1

    Gene LinkOut

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