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    PLA2-BETA phospholipase A2-beta [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816488, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PLA2-BETA
    Official Full Name
    phospholipase A2-beta
    Primary source
    TAIR:AT2G19690
    Locus tag
    AT2G19690
    See related
    Araport:AT2G19690
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F6F22.28; F6F22_28; phospholipase A2-beta
    Summary
    Encodes one of the four Arabidopsis phospholipase PLA2 parologs: AT2G06925 (PLA2-ALPHA), AT2G19690 (PLA2-BETA), AT4G29460 (PLA2-GAMMA) and AT4G29470 (PLA2-DELTA). Involved in pollen development and germination and tube growth. Also involved in stomatal opening in response to light.
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    Genomic context

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    See PLA2-BETA in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (8503217..8504924)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Cysteine/Histidine-rich C1 domain family protein Neighboring gene protein arginine methyltransferase 1A Neighboring gene Mitochondrial ATP synthase subunit G protein Neighboring gene uncharacterized protein Neighboring gene Regulator of Vps4 activity in the MVB pathway protein Neighboring gene ribosomal protein S15A B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phospholipase A2beta mediates light-induced stomatal opening in Arabidopsis. Seo J, et al. J Exp Bot, 2008. PMID 18725378, Free PMC Article
    2. Secretory low molecular weight phospholipase A2 plays important roles in cell elongation and shoot gravitropism in Arabidopsis. Lee HY, et al. Plant Cell, 2003 Sep. PMID 12953106, Free PMC Article
    3. Phospholipase A(2) is required for PIN-FORMED protein trafficking to the plasma membrane in the Arabidopsis root. Lee OR, et al. Plant Cell, 2010 Jun. PMID 20525850, Free PMC Article
    4. Endoplasmic reticulum- and Golgi-localized phospholipase A2 plays critical roles in Arabidopsis pollen development and germination. Kim HJ, et al. Plant Cell, 2011 Jan. PMID 21278126, Free PMC Article
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PLA(2) paralogs -beta, -gamma, and -delta expressed during pollen development, localize to the endoplasmic reticulum and/or Golgi, and play critical roles in pollen development and germination and tube growth.
      Title: Endoplasmic reticulum- and Golgi-localized phospholipase A2 plays critical roles in Arabidopsis pollen development and germination.
    2. PLA(2)beta is involved in light-induced stomatal opening in Arabidopsis.
      Title: Phospholipase A2beta mediates light-induced stomatal opening in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    NM_001202625.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phospholipase A2 activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phospholipase A2 activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in arachidonate secretion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in gravitropism IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phospholipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within pollen development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in pollen germination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in pollen tube growth IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of stomatal movement IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to auxin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to light stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    phospholipase A2-beta
    NP_001189554.1
    • phospholipase A2-beta (PLA2-BETA); FUNCTIONS IN: phospholipase A2 activity, calcium ion binding; INVOLVED IN: response to light stimulus, regulation of stomatal movement; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: vascular tissue, leaf mesophyll, guard cell; CONTAINS InterPro DOMAIN/s: Phospholipase A2, active site (InterPro:IPR013090), Phospholipase A2 (InterPro:IPR016090), Phospholipase A2, eukaryotic (InterPro:IPR001211); BEST Arabidopsis thaliana protein match is: Phospholipase A2 family protein (TAIR:AT4G29460.1).
    NP_179559.2
    • phospholipase A2-beta (PLA2-BETA); FUNCTIONS IN: phospholipase A2 activity, calcium ion binding; INVOLVED IN: response to light stimulus, regulation of stomatal movement; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: vascular tissue, leaf mesophyll, guard cell; CONTAINS InterPro DOMAIN/s: Phospholipase A2, active site (InterPro:IPR013090), Phospholipase A2 (InterPro:IPR016090), Phospholipase A2, eukaryotic (InterPro:IPR001211); BEST Arabidopsis thaliana protein match is: Phospholipase A2 family protein (TAIR:AT4G29460.1); Has 389 Blast hits to 389 proteins in 80 species: Archae - 0; Bacteria - 29; Metazoa - 247; Fungi - 0; Plants - 108; Viruses - 0; Other Eukaryotes - 5 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      8503217..8504924
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127527.4 → NP_179559.2  phospholipase A2-beta [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179559.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82208, Q8GZB4
      UniProtKB/TrEMBL
      A0A178VM42, A0A5S9WZI8, A0A7G2E9H3
      Conserved Domains (1) summary
      cd04706
      Location:25 → 143
      PLA2_plant; Plant-specific sub-family of Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. Enzymatically active PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids; ...

    2. NM_001335642.1 → NP_001325352.1  phospholipase A2-beta [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B2X2

    3. NM_001202625.1 → NP_001189554.1  phospholipase A2-beta [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189554.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2E9H3, F4ITF6
      Conserved Domains (1) summary
      cd04706
      Location:25 → 139
      PLA2_plant; PLA2_plant: Plant-specific sub-family of Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. Enzymatically active PLA2 cleaves the sn-2 position of the glycerol backbone of ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8GZB4.1

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