XIK myosin family protein with Dil [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: XIK
Official Full Name: myosin family protein with Dil
Primary source: TAIR:AT5G20490
Locus tag: AT5G20490
See related: Araport:AT5G20490
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATXIK; F7C8.80; F7C8_80; MYOSIN XI K; MYOSIN XI-17; XI-17; XI-K
Summary: Encodes a member of the type XI myosin protein family involved in root hair growth, trichome development, and organelle trafficking. Required for fast root hair growth. This gene appears to be expressed at low levels throughout the plant.
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Genomic context

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See XIK in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 39

Sequence:: Chromosome: 5; NC_003076.8 (6926516..6937830, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Arabidopsis thaliana myosin XIK is recruited to the Golgi through interaction with a MyoB receptor.
Title: Arabidopsis thaliana myosin XIK is recruited to the Golgi through interaction with a MyoB receptor.
Organelle movement and apical accumulation of secretory vesicles in pollen tubes of Arabidopsis thaliana depend on class XI myosins.
Title: Organelle movement and apical accumulation of secretory vesicles in pollen tubes of Arabidopsis thaliana depend on class XI myosins.
Interestingly, myosin XI-K:YFP (yellow fluorescent protein) was localized to the cell division apparatus in the root and shoot meristems. In anaphase and early telophase, XI-K:YFP was concentrated in the midzone and the forming cell plate. In late telophase, XI-K:YFP formed a ring that overlapped with the growing phragmoplast.
Title: Myosin XI-K is involved in root organogenesis, polar auxin transport, and cell division.
findings establish myosins XI as key regulators of plant antifungal immunity.
Title: Myosins XI modulate host cellular responses and penetration resistance to fungal pathogens.
By performing coexpression studies with AtDCP1, dominant-negative myosin fragments, as well as functional full-length myosin XI-K, the association of P-bodies and myosins was analyzed in detail.
Title: Processing-body movement in Arabidopsis depends on an interaction between myosins and DECAPPING PROTEIN1.
The class XI myosins XI-K, XI-1 and XI-2 have partially redundant roles in the growth of shoot epidermis. Myosin XI-K plays more important role whereas myosins XI-1 and XI-2 have minor roles in the determination of size and shape of epidermal cells.
Title: Myosins XI-K, XI-1, and XI-2 are required for development of pavement cells, trichomes, and stigmatic papillae in Arabidopsis.
Data suggest that the myosin XIK is required for normal actin dynamics and plays a role in the subapical region of growing root hairs to facilitate optimal growth.
Title: Myosin XIK of Arabidopsis thaliana accumulates at the root hair tip and is required for fast root hair growth.
a tail fragment of myosin XIK could inhibit the movement of several post-Golgi organelles, such as the trans-Golgi network, pre-vacuolar compartment, and endosomes, as well as total cytoplasmic streaming
Title: Myosin XIK is a major player in cytoplasm dynamics and is regulated by two amino acids in its tail.
Arabidopsis myosins XIE, and XIK, are involved in Golgi, peroxisome, and mitochondrial movement.
Title: Truncated myosin XI tail fusions inhibit peroxisome, Golgi, and mitochondrial movement in tobacco leaf epidermal cells: a genetic tool for the next generation.
knockouts exhibited defects in root hair elongation suggesting that the myosin-driven motility plays a significant role in a polar tip growth
Title: Two class XI myosins function in organelle trafficking and root hair development in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001161252.2

Supported by ESTs:

NM_001343670.1

Supported by ESTs:

NM_001343671.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables cytoskeletal motor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within Golgi localization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in actin filament organization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within actin filament-based movement	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within cell division	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within fruit development	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within gynoecium development	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within leaf pavement cell development	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within mitochondrion localization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within peroxisome localization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within post-embryonic development	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within root hair cell tip growth	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within root hair elongation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within trichome branching	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within trichome morphogenesis	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within trichome morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within unidimensional cell growth	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasmic stress granule	IDA Inferred from Direct Assay more info	PubMed
located_in plasmodesma	HDA more info	PubMed
located_in root hair tip	IDA Inferred from Direct Assay more info	PubMed
located_in transport vesicle	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: myosin family protein with Dil

NP_001318611.1

XIK; FUNCTIONS IN: motor activity; INVOLVED IN: in 11 processes; LOCATED IN: endomembrane system, myosin complex; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Dil domain (InterPro:IPR018444), Dilute (InterPro:IPR002710), Myosin, N-terminal, SH3-like (InterPro:IPR004009), Myosin head, motor domain (InterPro:IPR001609), IQ calmodulin-binding region (InterPro:IPR000048); BEST Arabidopsis thaliana protein match is: Myosin family protein with Dil domain (TAIR:AT1G54560.1); Has 40570 Blast hits to 26875 proteins in 2480 species: Archae - 466; Bacteria - 5527; Metazoa - 21427; Fungi - 3168; Plants - 2202; Viruses - 135; Other Eukaryotes - 7645 (source: NCBI BLink).

NP_001318612.1

XIK; FUNCTIONS IN: motor activity; INVOLVED IN: in 11 processes; LOCATED IN: myosin complex; EXPRESSED IN: stem, fruit, flower, root, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Dil domain (InterPro:IPR018444), Dilute (InterPro:IPR002710), Myosin head, motor domain (InterPro:IPR001609), IQ calmodulin-binding region (InterPro:IPR000048); BEST Arabidopsis thaliana protein match is: Myosin family protein with Dil domain (TAIR:AT1G54560.1); Has 39115 Blast hits to 25959 proteins in 2421 species: Archae - 443; Bacteria - 5231; Metazoa - 20936; Fungi - 2937; Plants - 2132; Viruses - 125; Other Eukaryotes - 7311 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

6926516..6937830 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001343671.1 → NP_001318612.1 myosin family protein with Dil [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/Swiss-Prot

E9N630, F4K5J1, F4K5J2, K9KY88, Q0WQJ2

UniProtKB/TrEMBL

A0A5S9Y5V7, A0A654G2W9
NM_001161252.2 → NP_001154724.1 myosin family protein with Dil [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001154724.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8BCY2, A0A5S9Y5V7, A0A654G2W9

Conserved Domains (4) summary

smart00242
Location:1 → 665

MYSc; Myosin. Large ATPases

cd15475
Location:1044 → 1427

MyosinXI_CBD; cargo binding domain of myosin XI

cd01384
Location:10 → 654

MYSc_Myo11; class XI myosin, motor domain

cl00817
Location:832 → 940

MM_CoA_mutase; Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM)-like family; contains proteins similar to MCM, and the large subunit of Streptomyces coenzyme B12-dependent isobutyryl-CoA mutase (ICM). MCM catalyzes the isomerization of ...
NM_001343670.1 → NP_001318611.1 myosin family protein with Dil, partial [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A5S9Y5V7, A0A654G2W9