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    DCI1 delta(3,5),delta(2,4)-dienoyl-CoA isomerase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834346, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DCI1
    Official Full Name
    delta(3,5),delta(2,4)-dienoyl-CoA isomerase 1
    Primary source
    TAIR:AT5G43280
    Locus tag
    AT5G43280
    See related
    Araport:AT5G43280
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ''delta(3; 4)-DIENOYL-; 4)-dienoyl-CoA isomerase 1; 4)-DIENOYL-COA ISOMERASE 1; 4)-dienoyl-CoA isomerase 1''; 5); ATDCI1; delta(2; DELTA(2; delta(3; DELTA(3; MNL12.10; MNL12_10
    Summary
    Encodes the peroxisomal delta 3,5-delta2,4-dienoyl-CoA isomerase, a enzyme involved in degradation of unsaturated fatty acids. Gene expression is induced upon seed germination.
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    Genomic context

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    See DCI1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (17367827..17369510)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene chaperone protein dnaJ-like protein Neighboring gene squamosa promoter binding protein-like 2 Neighboring gene Putative membrane lipoprotein Neighboring gene WRKY DNA-binding protein 49

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular identification and characterization of the Arabidopsis delta(3,5),delta(2,4)-dienoyl-coenzyme A isomerase, a peroxisomal enzyme participating in the beta-oxidation cycle of unsaturated fatty acids. Goepfert S, et al. Plant Physiol, 2005 Aug. PMID 16040662, Free PMC Article
    2. Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms. Reumann S, et al. Plant Cell, 2007 Oct. PMID 17951448, Free PMC Article
    3. Proximity labeling of protein complexes and cell-type-specific organellar proteomes in Arabidopsis enabled by TurboID. Mair A, et al. Elife, 2019 Sep 19. PMID 31535972, Free PMC Article
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001085229.1
    NM_123694.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid beta-oxidation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in fatty acid beta-oxidation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within fatty acid catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in peroxisome HDA PubMed 
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    delta(3,5),delta(2,4)-dienoyl-CoA isomerase 1
    NP_001078698.1
    • ''delta(3,5),delta(2,4)-dienoyl-CoA isomerase 1'' (DCI1); FUNCTIONS IN: enoyl-CoA hydratase activity, delta3,5-delta2,4-dienoyl-CoA isomerase activity; INVOLVED IN: fatty acid catabolic process, seed germination, metabolic process; LOCATED IN: peroxisome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Enoyl-CoA hydratase/isomerase, conserved site (InterPro:IPR018376), Crotonase, core (InterPro:IPR001753); BEST Arabidopsis thaliana protein match is: ATP-dependent caseinolytic (Clp) protease/crotonase family protein (TAIR:AT4G16800.1); Has 36679 Blast hits to 36669 proteins in 2260 species: Archae - 469; Bacteria - 24045; Metazoa - 1683; Fungi - 913; Plants - 624; Viruses - 0; Other Eukaryotes - 8945 (source: NCBI BLink).
    NP_199142.1
    • ''delta(3,5),delta(2,4)-dienoyl-CoA isomerase 1'' (DCI1); FUNCTIONS IN: enoyl-CoA hydratase activity, delta3,5-delta2,4-dienoyl-CoA isomerase activity; INVOLVED IN: fatty acid catabolic process, seed germination, metabolic process; LOCATED IN: peroxisome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Enoyl-CoA hydratase/isomerase, conserved site (InterPro:IPR018376), Crotonase, core (InterPro:IPR001753); BEST Arabidopsis thaliana protein match is: ATP-dependent caseinolytic (Clp) protease/crotonase family protein (TAIR:AT4G16800.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      17367827..17369510
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123694.4 → NP_199142.1  delta(3,5),delta(2,4)-dienoyl-CoA isomerase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199142.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8MRJ9, Q9FHR8
      UniProtKB/TrEMBL
      A0A5S9YB50, A0A654G833
      Conserved Domains (1) summary
      PLN02664
      Location:3 → 278
      PLN02664; enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase

    2. NM_001085229.1 → NP_001078698.1  delta(3,5),delta(2,4)-dienoyl-CoA isomerase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078698.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FHR8
      Conserved Domains (1) summary
      cl23717
      Location:3 → 215
      crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FHR8.1

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