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    BRC1 TCP family transcription factor [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821386, updated on 18-Sep-2024

    Summary

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    Official Symbol
    BRC1
    Official Full Name
    TCP family transcription factor
    Primary source
    TAIR:AT3G18550
    Locus tag
    AT3G18550
    See related
    Araport:AT3G18550
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtBRC1; ATTCP18; BRANCHED 1; TCP18
    Summary
    Encodes a TCP transcription factor, closely related to teosinte branched1, arrests axillary bud development and prevents axillary bud outgrowth.
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    Genomic context

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    See BRC1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (6383289..6385815)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ARM repeat superfamily protein Neighboring gene tubulin-tyrosine ligase Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A gene regulatory network critical for axillary bud dormancy directly controlled by Arabidopsis BRANCHED1. van Es SW, et al. New Phytol, 2024 Feb. PMID 38009929
    2. Connective auxin transport contributes to strigolactone-mediated shoot branching control independent of the transcription factor BRC1. van Rongen M, et al. PLoS Genet, 2019 Mar. PMID 30865619, Free PMC Article
    3. Phytoplasma effector SWP1 induces witches' broom symptom by destabilizing the TCP transcription factor BRANCHED1. Wang N, et al. Mol Plant Pathol, 2018 Dec. PMID 30047227, Free PMC Article
    4. BRC1 expression regulates bud activation potential but is not necessary or sufficient for bud growth inhibition in Arabidopsis. Seale M, et al. Development, 2017 May 1. PMID 28289131, Free PMC Article
    5. BRANCHED1 promotes axillary bud dormancy in response to shade in Arabidopsis. González-Grandío E, et al. Plant Cell, 2013 Mar. PMID 23524661, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Class I TCP transcription factors TCP14 and TCP15 promote axillary branching in Arabidopsis by counteracting the action of Class II TCP BRANCHED1.
      Title: Class I TCP transcription factors TCP14 and TCP15 promote axillary branching in Arabidopsis by counteracting the action of Class II TCP BRANCHED1.
    2. A gene regulatory network critical for axillary bud dormancy directly controlled by Arabidopsis BRANCHED1.
      Title: A gene regulatory network critical for axillary bud dormancy directly controlled by Arabidopsis BRANCHED1.
    3. The branchy phenotype of mutants lacking the axillary meristem-expressed transcription factor, BRANCHED1 (BRC1) is unaffected by pin3pin4pin7.
      Title: Connective auxin transport contributes to strigolactone-mediated shoot branching control independent of the transcription factor BRC1.
    4. These findings suggest that the phytoplasma effector SWP1 induces witches' broom symptoms through targeting of BRC1 and promoting its degradation.
      Title: Phytoplasma effector SWP1 induces witches' broom symptom by destabilizing the TCP transcription factor BRANCHED1.
    5. results reveal that TIE1 is an important shoot branching regulator, and provide new insights in the post-transcriptional regulation of the TCP transcription factor BRC1
      Title: The TIE1 transcriptional repressor controls shoot branching by directly repressing BRANCHED1 in Arabidopsis.
    6. a coherent feed-forward loop in which strigolactone treatment reduces the probability of bud activation by parallel effects on BRC1 transcription and the shoot auxin transport network.
      Title: BRC1 expression regulates bud activation potential but is not necessary or sufficient for bud growth inhibition in Arabidopsis.
    7. The Arabidopsis thaliana gene BRANCHED1 (BRC1), expressed in axillary buds, is required for branch suppression in response to shade.
      Title: BRANCHED1 promotes axillary bud dormancy in response to shade in Arabidopsis.
    8. Data indicate that BRANCHED1 (BRC1) interacts with the florigen proteins FLOWERING LOCUS T (FT) and TWIN SISTER OF FT (TSF) but not with TERMINAL FLOWER1, a floral repressor.
      Title: BRANCHED1 interacts with FLOWERING LOCUS T to repress the floral transition of the axillary meristems in Arabidopsis.
    9. BRANCHED1 (BRC1) plays a central role in the control of axillary bud development. BRC1 acts as a local integrator of the genetic pathways controlling branch outgrowth. [BRC1]
      Title: Arabidopsis BRANCHED1 acts as an integrator of branching signals within axillary buds.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001125184.1
    NM_001338345.1
    NM_112741.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of secondary shoot formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within secondary shoot formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in secondary shoot formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    TCP family transcription factor
    NP_001118656.1
    • BRANCHED 1 (BRC1); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of secondary shoot formation, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: axillary bud, axillary bud meristem; CONTAINS InterPro DOMAIN/s: Transcription factor, TCP (InterPro:IPR005333), CYC/TB1, R domain (InterPro:IPR017888), Transcription factor TCP subgroup (InterPro:IPR017887); BEST Arabidopsis thaliana protein match is: TCP domain protein 12 (TAIR:AT1G68800.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001319582.1
    • BRANCHED 1 (BRC1); CONTAINS InterPro DOMAIN/s: Transcription factor, TCP (InterPro:IPR005333), CYC/TB1, R domain (InterPro:IPR017888), Transcription factor TCP subgroup (InterPro:IPR017887); BEST Arabidopsis thaliana protein match is: TCP domain protein 12 (TAIR:AT1G68800.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      6383289..6385815
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001338346.1 → NP_001327556.1  TCP family transcription factor [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LSP1, A0A7G2EMY1

    2. NM_001338345.1 → NP_001319582.1  TCP family transcription factor [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0AQW3, A1YKT1, Q9LII4
      UniProtKB/TrEMBL
      A0A654F8H0, A0A7G2EMY1
      Conserved Domains (1) summary
      pfam03634
      Location:146 → 301
      TCP; TCP family transcription factor

    3. NM_001125184.1 → NP_001118656.1  TCP family transcription factor [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001118656.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2EMY1
      Conserved Domains (1) summary
      pfam03634
      Location:147 → 297
      TCP; TCP family transcription factor

    4. NM_112741.3 → NP_188485.2  TCP family transcription factor [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188485.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0AQW3, A1YKT1, Q9LII4
      UniProtKB/TrEMBL
      A0A654F8H0, A0A7G2EMY1
      Conserved Domains (1) summary
      pfam03634
      Location:146 → 301
      TCP; TCP family transcription factor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1YKT1.1

    Gene LinkOut

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