U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    BCAT-2 branched-chain amino acid transaminase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837543, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    BCAT-2
    Official Full Name
    branched-chain amino acid transaminase 2
    Primary source
    TAIR:AT1G10070
    Locus tag
    AT1G10070
    See related
    Araport:AT1G10070
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATBCAT-2; BCAT2; branched-chain amino acid transaminase 2; branched-chain amino acid transferase 2; T27I1.9; T27I1_9
    Summary
    Encodes a chloroplast branched-chain amino acid aminotransferase. Complements the yeast leu/iso-leu/val auxotrophy mutant. Involved in cell wall development.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See BCAT-2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (3288087..3290471)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene glycosyl hydrolase family 10 protein / carbohydrate-binding domain-containing protein Neighboring gene branched-chain amino acid transaminase 1 Neighboring gene Early-responsive to dehydration stress protein (ERD4) Neighboring gene Protein prenylyltransferase superfamily protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genome-wide analysis of branched-chain amino acid levels in Arabidopsis seeds. Angelovici R, et al. Plant Cell, 2013 Dec. PMID 24368787, Free PMC Article
    2. The branched-chain amino acid transaminase gene family in Arabidopsis encodes plastid and mitochondrial proteins. Diebold R, et al. Plant Physiol, 2002 Jun. PMID 12068099, Free PMC Article
    3. A role for BELLRINGER in cell wall development is supported by loss-of-function phenotypes. Etchells JP, et al. BMC Plant Biol, 2012 Nov 13. PMID 23148846, Free PMC Article
    4. A mesoscale abscisic acid hormone interactome reveals a dynamic signaling landscape in Arabidopsis. Lumba S, et al. Dev Cell, 2014 May 12. PMID 24823379
    5. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. BCAT2 is the causal gene driving seed branched-chain amino acid natural variation.
      Title: Genome-wide analysis of branched-chain amino acid levels in Arabidopsis seeds.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_001035938.2
    NM_001035939.3
    NM_100881.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables L-isoleucine-2-oxoglutarate transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables L-leucine-2-oxoglutarate transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables L-valine-2-oxoglutarate transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables branched-chain-amino-acid transaminase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-leucine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in L-valine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in isoleucine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within plant-type cell wall organization or biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    branched-chain amino acid transaminase 2
    NP_001031015.1
    • branched-chain amino acid transaminase 2 (BCAT-2); FUNCTIONS IN: branched-chain-amino-acid transaminase activity, catalytic activity; INVOLVED IN: branched chain family amino acid metabolic process, metabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Aminotransferase, class IV (InterPro:IPR001544), Aminotransferase, class IV, conserved site (InterPro:IPR018300), Branched-chain amino acid aminotransferase II (InterPro:IPR005786); BEST Arabidopsis thaliana protein match is: branched-chain amino acid aminotransferase 5 / branched-chain amino acid transaminase 5 (BCAT5) (TAIR:AT5G65780.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_001031016.2
    • branched-chain amino acid transaminase 2 (BCAT-2); FUNCTIONS IN: branched-chain-amino-acid transaminase activity, catalytic activity; INVOLVED IN: branched chain family amino acid metabolic process, metabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Aminotransferase, class IV (InterPro:IPR001544), Aminotransferase, class IV, conserved site (InterPro:IPR018300), Branched-chain amino acid aminotransferase II (InterPro:IPR005786); BEST Arabidopsis thaliana protein match is: branched-chain amino acid aminotransferase 5 / branched-chain amino acid transaminase 5 (BCAT5) (TAIR:AT5G65780.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_172478.1
    • branched-chain amino acid transaminase 2 (BCAT-2); FUNCTIONS IN: branched-chain-amino-acid transaminase activity, catalytic activity; INVOLVED IN: branched chain family amino acid metabolic process, metabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Aminotransferase, class IV (InterPro:IPR001544), Aminotransferase, class IV, conserved site (InterPro:IPR018300), Branched-chain amino acid aminotransferase II (InterPro:IPR005786); BEST Arabidopsis thaliana protein match is: branched-chain amino acid aminotransferase 5 / branched-chain amino acid transaminase 5 (BCAT5) (TAIR:AT5G65780.1); Has 12153 Blast hits to 12153 proteins in 2497 species: Archae - 154; Bacteria - 7615; Metazoa - 264; Fungi - 416; Plants - 254; Viruses - 0; Other Eukaryotes - 3450 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      3288087..3290471
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100881.3 → NP_172478.1  branched-chain amino acid transaminase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172478.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80598, Q9M439
      UniProtKB/TrEMBL
      A0A5S9TK02, A0A654E8C8, B9DHH5
      Conserved Domains (2) summary
      PLN02259
      Location:1 → 388
      PLN02259; branched-chain-amino-acid aminotransferase 2
      cd01557
      Location:94 → 375
      BCAT_beta_family; BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and ...

    2. NM_001035939.3 → NP_001031016.2  branched-chain amino acid transaminase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031016.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9TK02, A0A654E8C8, Q2V4P2
      Conserved Domains (2) summary
      PRK13357
      Location:1 → 317
      PRK13357; branched-chain amino acid aminotransferase; Provisional
      cd01557
      Location:24 → 305
      BCAT_beta_family; BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and ...

    3. NM_001035938.2 → NP_001031015.1  branched-chain amino acid transaminase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031015.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80598, Q9M439
      UniProtKB/TrEMBL
      A0A5S9TK02, A0A654E8C8, B9DHH5
      Conserved Domains (2) summary
      PLN02259
      Location:1 → 388
      PLN02259; branched-chain-amino-acid aminotransferase 2
      cd01557
      Location:94 → 375
      BCAT_beta_family; BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M439.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.