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    BBD1 bifunctional nuclease in basal defense response 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843874, updated on 18-Sep-2024

    Summary

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    Official Symbol
    BBD1
    Official Full Name
    bifunctional nuclease in basal defense response 1
    Primary source
    TAIR:AT1G75380
    Locus tag
    AT1G75380
    See related
    Araport:AT1G75380
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATBBD1; bifunctional nuclease in basal defense response 1; F1B16.9; F1B16_9
    Summary
    Encodes a nuclease involved in ABA-mediated callose deposition. It has been shown to interact with JAZ proteins, binds to a jasmonic acid-responsive element (JARE) and repress AtJMT expression.
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    Genomic context

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    See BBD1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Sequence:
    Chromosome: 1; NC_003070.9 (28281195..28284168, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Zinc finger C-x8-C-x5-C-x3-H type family protein Neighboring gene Ribosomal protein L31 Neighboring gene uncharacterized protein Neighboring gene Sec14p-like phosphatidylinositol transfer family protein Neighboring gene ncRNA Neighboring gene basic leucine-zipper 44

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Overexpression of AtBBD1, Arabidopsis Bifunctional Nuclease, Confers Drought Tolerance by Enhancing the Expression of Regulatory Genes in ABA-Mediated Drought Stress Signaling. Huque AKMM, et al. Int J Mol Sci, 2021 Mar 13. PMID 33805821, Free PMC Article
    2. Phylogenetic Analysis and In Vitro Bifunctional Nuclease Assay of Arabidopsis BBD1 and BBD2. Huque AKMM, et al. Molecules, 2020 May 6. PMID 32384799, Free PMC Article
    3. Novel bifunctional nucleases, OmBBD and AtBBD1, are involved in abscisic acid-mediated callose deposition in Arabidopsis. You MK, et al. Plant Physiol, 2010 Feb. PMID 20018603, Free PMC Article
    4. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Overexpression of AtBBD1, Arabidopsis Bifunctional Nuclease, Confers Drought Tolerance by Enhancing the Expression of Regulatory Genes in ABA-Mediated Drought Stress Signaling.
      Title: Overexpression of AtBBD1, Arabidopsis Bifunctional Nuclease, Confers Drought Tolerance by Enhancing the Expression of Regulatory Genes in ABA-Mediated Drought Stress Signaling.
    2. Phylogenetic Analysis and In Vitro Bifunctional Nuclease Assay of Arabidopsis BBD1 and BBD2.
      Title: Phylogenetic Analysis and In Vitro Bifunctional Nuclease Assay of Arabidopsis BBD1 and BBD2.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_106192.3
    NM_179559.3
    NM_179560.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA nuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables deoxyribonuclease I activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables nuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within abscisic acid-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of stomatal movement IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bifunctional nuclease in basal defense response 1
    NP_177671.1
    • bifunctional nuclease in basal defense response 1 (BBD1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF151 (InterPro:IPR003729), UvrB/UvrC protein (InterPro:IPR001943); BEST Arabidopsis thaliana protein match is: Wound-responsive family protein (TAIR:AT1G19660.2); Has 843 Blast hits to 843 proteins in 291 species: Archae - 44; Bacteria - 501; Metazoa - 0; Fungi - 0; Plants - 105; Viruses - 0; Other Eukaryotes - 193 (source: NCBI BLink).
    NP_849890.1
    • bifunctional nuclease in basal defense response 1 (BBD1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF151 (InterPro:IPR003729), UvrB/UvrC protein (InterPro:IPR001943); BEST Arabidopsis thaliana protein match is: Wound-responsive family protein (TAIR:AT1G19660.2); Has 843 Blast hits to 843 proteins in 291 species: Archae - 44; Bacteria - 501; Metazoa - 0; Fungi - 0; Plants - 105; Viruses - 0; Other Eukaryotes - 193 (source: NCBI BLink).
    NP_849891.1
    • bifunctional nuclease in basal defense response 1 (BBD1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF151 (InterPro:IPR003729), UvrB/UvrC protein (InterPro:IPR001943); BEST Arabidopsis thaliana protein match is: Wound-responsive family protein (TAIR:AT1G19660.2); Has 843 Blast hits to 843 proteins in 291 species: Archae - 44; Bacteria - 501; Metazoa - 0; Fungi - 0; Plants - 105; Viruses - 0; Other Eukaryotes - 193 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      28281195..28284168 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001334685.1 → NP_001322708.1  bifunctional nuclease in basal defense response 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FWS6
      UniProtKB/TrEMBL
      A0A178WDF6, A0A5S9WUN5
      Conserved Domains (2) summary
      pfam02151
      Location:291 → 318
      UVR; UvrB/uvrC motif
      cl00553
      Location:136 → 241
      DNase-RNase; Bifunctional nuclease

    2. NM_179559.3 → NP_849890.1  bifunctional nuclease in basal defense response 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849890.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FWS6
      UniProtKB/TrEMBL
      A0A178WDF6, A0A5S9WUN5
      Conserved Domains (2) summary
      pfam02151
      Location:291 → 318
      UVR; UvrB/uvrC motif
      cl00553
      Location:136 → 241
      DNase-RNase; Bifunctional nuclease

    3. NM_106192.3 → NP_177671.1  bifunctional nuclease in basal defense response 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177671.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FWS6
      UniProtKB/TrEMBL
      A0A178WDF6, A0A5S9WUN5
      Conserved Domains (2) summary
      pfam02151
      Location:291 → 318
      UVR; UvrB/uvrC motif
      cl00553
      Location:136 → 241
      DNase-RNase; Bifunctional nuclease

    4. NM_179560.3 → NP_849891.1  bifunctional nuclease in basal defense response 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849891.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FWS6
      UniProtKB/TrEMBL
      A0A178WDF6, A0A5S9WUN5
      Conserved Domains (2) summary
      pfam02151
      Location:291 → 318
      UVR; UvrB/uvrC motif
      cl00553
      Location:136 → 241
      DNase-RNase; Bifunctional nuclease
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FWS6.1

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