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    Trimeric LpxA-like enzyme [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818061, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Trimeric LpxA-like enzyme
    Primary source
    TAIR:AT2G34970
    Locus tag
    AT2G34970
    See related
    Araport:AT2G34970
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F19I3.20; F19I3_20
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (14746236..14748783)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene tRNA-Thr Neighboring gene cationic amino acid transporter 5 Neighboring gene phosphatidylinositolglycan synthase family protein Neighboring gene tRNA-Thr

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Capturing the phosphorylation and protein interaction landscape of the plant TOR kinase. Van Leene J, et al. Nat Plants, 2019 Mar. PMID 30833711
    2. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_129049.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables translation initiation factor binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Trimeric LpxA-like enzyme
    NP_181042.1
    • Trimeric LpxA-like enzyme; FUNCTIONS IN: binding, transferase activity, translation initiation factor activity, nucleotidyltransferase activity; INVOLVED IN: biosynthetic process, regulation of translational initiation; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Trimeric LpxA-like (InterPro:IPR011004), eIF4-gamma/eIF5/eIF2-epsilon (InterPro:IPR003307), Armadillo-type fold (InterPro:IPR016024), Nucleotidyl transferase (InterPro:IPR005835); BEST Arabidopsis thaliana protein match is: Trimeric LpxA-like enzyme (TAIR:AT4G18300.1); Has 8121 Blast hits to 7961 proteins in 1548 species: Archae - 574; Bacteria - 3735; Metazoa - 1296; Fungi - 469; Plants - 387; Viruses - 0; Other Eukaryotes - 1660 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      14746236..14748783
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129049.3 → NP_181042.1  Trimeric LpxA-like enzyme [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181042.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9X3Z7, A0A654EZ00, O64760
      Conserved Domains (4) summary
      cd05787
      Location:348 → 426
      LbH_eIF2B_epsilon; eIF-2B epsilon subunit, central Left-handed parallel beta-Helix (LbH) domain: eIF-2B is a eukaryotic translation initiator, a guanine nucleotide exchange factor (GEF) composed of five different subunits (alpha, beta, gamma, delta and epsilon). eIF2B is ...
      cd04197
      Location:25 → 246
      eIF-2B_epsilon_N; The N-terminal domain of epsilon subunit of the eIF-2B is a subfamily of glycosyltransferase 2
      cd11558
      Location:550 → 714
      W2_eIF2B_epsilon; C-terminal W2 domain of eukaryotic translation initiation factor 2B epsilon
      COG1208
      Location:26 → 425
      GCD1; NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins [Translation, ribosomal structure and biogenesis, Cell wall/membrane/envelope biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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