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    Zincin-like metalloproteases family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830919, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Zincin-like metalloproteases family protein
    Primary source
    TAIR:AT5G10540
    Locus tag
    AT5G10540
    See related
    Araport:AT5G10540
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F12B17.110; F12B17_110; thimet metalloendopeptidase 2; TOP2
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    18
    Sequence:
    Chromosome: 5; NC_003076.8 (3324812..3334971)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene AINTEGUMENTA-like 6 Neighboring gene ROP binding protein kinases 1 Neighboring gene tRNA-Arg Neighboring gene Concanavalin A-like lectin protein kinase family protein Neighboring gene ncRNA Neighboring gene global transcription factor group E2 Neighboring gene miscRNA Neighboring gene Glycosyl hydrolase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Proteome-Wide Analysis of Cysteine Reactivity during Effector-Triggered Immunity. McConnell EW, et al. Plant Physiol, 2019 Apr. PMID 30510037, Free PMC Article
    2. The Arabidopsis oligopeptidases TOP1 and TOP2 are salicylic acid targets that modulate SA-mediated signaling and the immune response. Moreau M, et al. Plant J, 2013 Nov. PMID 24004003
    3. Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics; an oxidative stress case study. Bindschedler LV, et al. Phytochemistry, 2008 Jul. PMID 18538804
    4. Isolation and identification of ubiquitin-related proteins from Arabidopsis seedlings. Igawa T, et al. J Exp Bot, 2009. PMID 19429840, Free PMC Article
    5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. role in maintaining the proper level and dynamics of proteome oxidation during effector-triggered immunity
      Title: Proteome-Wide Analysis of Cysteine Reactivity during Effector-Triggered Immunity.
    2. Interacts with protein targets to mediate salicylic acid (SA)-dependent signaling necessary for the immune response to avirulent pathogens.
      Title: The Arabidopsis oligopeptidases TOP1 and TOP2 are salicylic acid targets that modulate SA-mediated signaling and the immune response.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_121092.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in apoplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    Zincin-like metalloproteases family protein
    NP_568232.1
    • Zincin-like metalloproteases family protein; FUNCTIONS IN: metalloendopeptidase activity; INVOLVED IN: response to cadmium ion, proteolysis; LOCATED IN: cytosol, apoplast, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M3A/M3B, thimet/oligopeptidase F (InterPro:IPR001567); BEST Arabidopsis thaliana protein match is: Zincin-like metalloproteases family protein (TAIR:AT5G65620.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      3324812..3334971
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121092.4 → NP_568232.1  Zincin-like metalloproteases family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568232.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q949P2, Q9LXA6
      UniProtKB/TrEMBL
      A0A178UD97, A0A5S9Y587
      Conserved Domains (1) summary
      cd06456
      Location:28 → 696
      M3A_DCP; Peptidase family M3, dipeptidyl carboxypeptidase (DCP)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q949P2.1

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