PKP-ALPHA Pyruvate kinase family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: PKP-ALPHA
Official Full Name: Pyruvate kinase family protein
Primary source: TAIR:AT3G22960
Locus tag: AT3G22960
See related: Araport:AT3G22960
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: PKP1; PLASTIDIAL PYRUVATE KINASE 1
Summary: encodes a chloroplast pyruvate kinase alpha subunit. Important for seed oil biosynthesis. Ubiquitously expressed, with significantly increased expression in maturing seeds.
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Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_113196.3

Function	Evidence Code	Pubs
enables magnesium ion binding	IDA Inferred from Direct Assay more info	PubMed
enables potassium ion binding	IDA Inferred from Direct Assay more info	PubMed
enables pyruvate kinase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in glycolytic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within lipid metabolic process	IGI Inferred from Genetic Interaction more info	PubMed
involved_in seed maturation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in seed maturation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	IDA Inferred from Direct Assay more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in chloroplast stroma	HDA more info	PubMed
located_in chloroplast stroma	IDA Inferred from Direct Assay more info	PubMed
NOT located_in cytosol	RCA inferred from Reviewed Computational Analysis more info	PubMed

NP_566720.1

PKP-ALPHA; FUNCTIONS IN: pyruvate kinase activity; INVOLVED IN: response to cadmium ion, glycolysis, lipid metabolic process; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Pyruvate kinase, C-terminal-like (InterPro:IPR015795), Pyruvate kinase, active site (InterPro:IPR018209), Pyruvate kinase, beta-barrel-like (InterPro:IPR011037), Pyruvate kinase, alpha/beta (InterPro:IPR015794), Pyruvate/Phosphoenolpyruvate kinase, catalytic core (InterPro:IPR015813), Pyruvate kinase (InterPro:IPR001697), Pyruvate kinase, barrel (InterPro:IPR015793); BEST Arabidopsis thaliana protein match is: plastidic pyruvate kinase beta subunit 1 (TAIR:AT5G52920.1); Has 10289 Blast hits to 10239 proteins in 2715 species: Archae - 167; Bacteria - 6049; Metazoa - 538; Fungi - 221; Plants - 529; Viruses - 0; Other Eukaryotes - 2785 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain