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    DHDPS2 dihydrodipicolinate synthase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819152, updated on 18-Sep-2024

    Summary

    Official Symbol
    DHDPS2
    Official Full Name
    dihydrodipicolinate synthase
    Primary source
    TAIR:AT2G45440
    Locus tag
    AT2G45440
    See related
    Araport:AT2G45440
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    dihydrodipicolinate synthase; dihydrodipicolinate synthase 2; F4L23.5
    Summary
    Encodes a protein that likely has dihydropicolinate synthase activity based on its mutant phenotype of decreased lysine levels and increased aspartate levels. The mutant also has increased levels of threonine. The enzyme is predicted to localize to the chloroplast.
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    Genomic context

    See DHDPS2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (18730840..18733119)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene AT-hook motif nuclear-localized protein 22 Neighboring gene binding protein Neighboring gene SMAD/FHA domain-containing protein

    Bibliography

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    dihydrodipicolinate synthase
    NP_182068.1
    • dihydrodipicolinate synthase (DHDPS2); FUNCTIONS IN: dihydrodipicolinate synthase activity; INVOLVED IN: lysine biosynthetic process via diaminopimelate, metabolic process, diaminopimelate biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Dihydrodipicolinate synthase subfamily (InterPro:IPR005263), Dihydrodipicolinate synthetase (InterPro:IPR002220), Dihydrodipicolinate synthetase, active site (InterPro:IPR020625), Dihydrodipicolinate synthetase, conserved site (InterPro:IPR020624); BEST Arabidopsis thaliana protein match is: dihydrodipicolinate synthase 1 (TAIR:AT3G60880.2); Has 13334 Blast hits to 13334 proteins in 2656 species: Archae - 353; Bacteria - 9459; Metazoa - 101; Fungi - 305; Plants - 96; Viruses - 0; Other Eukaryotes - 3020 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18730840..18733119
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130106.3NP_182068.1  dihydrodipicolinate synthase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_182068.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22129, Q9FVC8
      UniProtKB/TrEMBL
      A0A178VXY0, A0A384KQ79, A0A654F7D0, A0A7G2EK59, Q0WSN6
      Conserved Domains (1) summary
      PLN02417
      Location:64343
      PLN02417; dihydrodipicolinate synthase