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    CYP79B2 cytochrome P450, family 79, subfamily B, polypeptide 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830154, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CYP79B2
    Official Full Name
    cytochrome P450, family 79, subfamily B, polypeptide 2
    Primary source
    TAIR:AT4G39950
    Locus tag
    AT4G39950
    See related
    Araport:AT4G39950
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ''cytochrome P450; cytochrome P450; family 79; polypeptide 2; polypeptide 2''; subfamily B; T5J17.120; T5J17_120
    Summary
    Belongs to cytochrome P450 and is involved in tryptophan metabolism. Converts Trp to indo-3-acetaldoxime (IAOx), a precursor to IAA and indole glucosinolates.
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    Genomic context

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    See CYP79B2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (18525042..18527602)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene APS-kinase 2 Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene alpha/beta-Hydrolases superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Trp-dependent auxin biosynthesis in Arabidopsis: involvement of cytochrome P450s CYP79B2 and CYP79B3. Zhao Y, et al. Genes Dev, 2002 Dec 1. PMID 12464638, Free PMC Article
    2. Disease resistance of Arabidopsis to Phytophthora brassicae is established by the sequential action of indole glucosinolates and camalexin. Schlaeppi K, et al. Plant J, 2010 Jun 1. PMID 20230487
    3. Sites and regulation of auxin biosynthesis in Arabidopsis roots. Ljung K, et al. Plant Cell, 2005 Apr. PMID 15772288, Free PMC Article
    4. Arabidopsis cytochrome P450s that catalyze the first step of tryptophan-dependent indole-3-acetic acid biosynthesis. Hull AK, et al. Proc Natl Acad Sci U S A, 2000 Feb 29. PMID 10681464, Free PMC Article
    5. Controlled indole-3-acetaldoxime production through ethanol-induced expression of CYP79B2. Mikkelsen MD, et al. Planta, 2009 May. PMID 19263076

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_120158.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within camalexin biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response by callose deposition in cell wall IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response to oomycetes IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within indoleacetic acid biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within indoleacetic acid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within induced systemic resistance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to insect IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within tryptophan catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast NAS
    Non-traceable Author Statement
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450, family 79, subfamily B, polypeptide 2
    NP_195705.1
    • ''cytochrome P450, family 79, subfamily B, polypeptide 2'' (CYP79B2); FUNCTIONS IN: electron carrier activity, monooxygenase activity, iron ion binding, oxygen binding, heme binding; INVOLVED IN: in 8 processes; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 79, subfamily B, polypeptide 3 (TAIR:AT2G22330.1); Has 28507 Blast hits to 28366 proteins in 1550 species: Archae - 44; Bacteria - 2565; Metazoa - 10705; Fungi - 5395; Plants - 8898; Viruses - 0; Other Eukaryotes - 900 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      18525042..18527602
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001342561.1 → NP_001328605.1  cytochrome P450, family 79, subfamily B, polypeptide 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B560, A0A654FX58

    2. NM_120158.2 → NP_195705.1  cytochrome P450, family 79, subfamily B, polypeptide 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195705.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81346, Q9SMR0
      UniProtKB/TrEMBL
      A0A178UZZ6, A0A5S9Y079
      Conserved Domains (1) summary
      PLN02971
      Location:1 → 541
      PLN02971; tryptophan N-hydroxylase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O81346.2

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