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    AGD8 ARF-GAP domain 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827512, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AGD8
    Official Full Name
    ARF-GAP domain 8
    Primary source
    TAIR:AT4G17890
    Locus tag
    AT4G17890
    See related
    Araport:AT4G17890
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARF-GAP domain 8; T6K21.1
    Summary
    A member of ARF GAP domain (AGD), A thaliana has 15 members, grouped into four classes.
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    Genomic context

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    See AGD8 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    7
    Sequence:
    Chromosome: 4; NC_003075.7 (9936861..9939493)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Polyketide cyclase/dehydrase and lipid transport superfamily protein Neighboring gene Basic helix-loop-helix (bHLH) DNA-binding family protein Neighboring gene ubiquitin-specific protease 20 Neighboring gene PLATZ transcription factor family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Recruitment of Arf1-GDP to Golgi by Glo3p-type ArfGAPs is crucial for golgi maintenance and plant growth. Min MK, et al. Plant Physiol, 2013 Feb. PMID 23266962, Free PMC Article
    2. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data indicate that ArfGAP domain8 (AGD8) and ARF-GAP domain 9 (AGD9), are involved in the recruitment of Arf1-GDP to the Golgi apparatus .
      Title: Recruitment of Arf1-GDP to Golgi by Glo3p-type ArfGAPs is crucial for golgi maintenance and plant growth.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001036581.1
    NM_117898.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ARF-GAP domain 8
    NP_001031658.1
    • ARF-GAP domain 8 (AGD8); FUNCTIONS IN: ARF GTPase activator activity, DNA binding, zinc ion binding; INVOLVED IN: regulation of ARF GTPase activity; LOCATED IN: nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Arf GTPase activating protein (InterPro:IPR001164); BEST Arabidopsis thaliana protein match is: ARF-GAP domain 9 (TAIR:AT5G46750.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_567543.1
    • ARF-GAP domain 8 (AGD8); FUNCTIONS IN: ARF GTPase activator activity, DNA binding, zinc ion binding; INVOLVED IN: regulation of ARF GTPase activity; LOCATED IN: nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Arf GTPase activating protein (InterPro:IPR001164); BEST Arabidopsis thaliana protein match is: ARF-GAP domain 9 (TAIR:AT5G46750.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      9936861..9939493
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117898.5 → NP_567543.1  ARF-GAP domain 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567543.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DG60, O49688, Q2V3H4, Q682W5, Q8H100, Q9C5L0
      UniProtKB/TrEMBL
      A0A178UXQ2, A0A5S9XTG9, A0A654FQC6
      Conserved Domains (1) summary
      PLN03114
      Location:5 → 405
      PLN03114; ADP-ribosylation factor GTPase-activating protein AGD10; Provisional

    2. NM_001036581.1 → NP_001031658.1  ARF-GAP domain 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031658.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654FQC6
      Conserved Domains (2) summary
      PLN03114
      Location:5 → 378
      PLN03114; ADP-ribosylation factor GTPase-activating protein AGD10; Provisional
      pfam01412
      Location:15 → 125
      ArfGap; Putative GTPase activating protein for Arf
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8H100.1

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