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    Hdgfl1 HDGF like 1 [ Mus musculus (house mouse) ]

    Gene ID: 15192, updated on 9-Dec-2024

    Summary

    Official Symbol
    Hdgfl1provided by MGI
    Official Full Name
    HDGF like 1provided by MGI
    Primary source
    MGI:MGI:1194493
    See related
    Ensembl:ENSMUSG00000045835 AllianceGenome:MGI:1194493
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    HRP-1; Pwwp1; Hdgfrp1; 4921520N01Rik
    Summary
    Predicted to be involved in chromatin remodeling. Predicted to be active in nucleus. Is expressed in central nervous system and ganglia. Orthologous to human HDGFL1 (HDGF like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Hdgfl1 in Genome Data Viewer
    Location:
    13; 13 A3.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (26952155..26954148, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (26768172..26770165, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700092E19 gene Neighboring gene STARR-seq mESC enhancer starr_34009 Neighboring gene STARR-seq mESC enhancer starr_34011 Neighboring gene STARR-seq mESC enhancer starr_34012 Neighboring gene ribosomal protein S8 pseudogene Neighboring gene 60S ribosomal protein L27a-like Neighboring gene STARR-seq mESC enhancer starr_34013 Neighboring gene STARR-seq mESC enhancer starr_34014 Neighboring gene prolactin

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Clone Names

    • MGC118278, MGC144483, MGC144484

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    hepatoma-derived growth factor-like protein 1
    Names
    PWWP domain containing 1
    hepatoma derived growth factor-like 1
    hepatoma-derived growth factor, related protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008232.3NP_032258.2  hepatoma-derived growth factor-like protein 1

      See identical proteins and their annotated locations for NP_032258.2

      Status: VALIDATED

      Source sequence(s)
      AL662807
      Consensus CDS
      CCDS26388.1
      UniProtKB/TrEMBL
      O35539, Q2VPR5
      Related
      ENSMUSP00000057557.4, ENSMUST00000055915.6
      Conserved Domains (1) summary
      cd05834
      Location:885
      HDGF_related; The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HPR1, ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      26952155..26954148 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)