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    Obp2a odorant binding protein 2A [ Mus musculus (house mouse) ]

    Gene ID: 227627, updated on 9-Dec-2024

    Summary

    Official Symbol
    Obp2aprovided by MGI
    Official Full Name
    odorant binding protein 2Aprovided by MGI
    Primary source
    MGI:MGI:2387617
    See related
    Ensembl:ENSMUSG00000062061 AllianceGenome:MGI:2387617
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Lcn13
    Summary
    Predicted to enable small molecule binding activity. Acts upstream of or within several processes, including insulin receptor signaling pathway; negative regulation of gluconeogenesis; and regulation of lipid metabolic process. Located in extracellular space. Orthologous to human OBP2B (odorant binding protein 2B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in genital fat pad adult (RPKM 6.0), adrenal adult (RPKM 1.1) and 1 other tissue See more
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    Genomic context

    See Obp2a in Genome Data Viewer
    Location:
    2 A3; 2 17.8 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (25587589..25593338)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (25697577..25703326)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene lipocalin 6 Neighboring gene lipocalin 10 Neighboring gene brain expressed myelocytomatosis oncogene Neighboring gene odorant binding protein 2B Neighboring gene predicted gene, 54106

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    odorant-binding protein 2a
    Names
    epididymal-specific lipocalin-13
    lipocalin 13

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153558.1NP_705786.1  odorant-binding protein 2a precursor

      See identical proteins and their annotated locations for NP_705786.1

      Status: VALIDATED

      Source sequence(s)
      BC027556
      Consensus CDS
      CCDS15788.1
      UniProtKB/Swiss-Prot
      Q8K1H9
      Related
      ENSMUSP00000076851.4, ENSMUST00000077667.4
      Conserved Domains (1) summary
      pfam00061
      Location:31166
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      25587589..25593338
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006497869.4XP_006497932.1  odorant-binding protein 2a isoform X1

      See identical proteins and their annotated locations for XP_006497932.1

      Conserved Domains (1) summary
      cd19414
      Location:71218
      lipocalin_1_3_4_13-like; lipocalin-1, -3, -4, -13 and similar proteins
    2. XM_006497868.4XP_006497931.1  odorant-binding protein 2a isoform X1

      See identical proteins and their annotated locations for XP_006497931.1

      Conserved Domains (1) summary
      cd19414
      Location:71218
      lipocalin_1_3_4_13-like; lipocalin-1, -3, -4, -13 and similar proteins
    3. XM_006497873.2XP_006497936.1  odorant-binding protein 2a isoform X2

      See identical proteins and their annotated locations for XP_006497936.1

      Conserved Domains (1) summary
      cd19414
      Location:1135
      lipocalin_1_3_4_13-like; lipocalin-1, -3, -4, -13 and similar proteins