ALDH7B4 aldehyde dehydrogenase 7B4 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ALDH7B4
Official Full Name: aldehyde dehydrogenase 7B4
Primary source: TAIR:AT1G54100
Locus tag: AT1G54100
See related: Araport:AT1G54100
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: aldehyde dehydrogenase 7B4; F15I1.19; F15I1_19
Summary: Aldehyde dehydrogenase
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Genomic context

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See ALDH7B4 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 15

Sequence:: Chromosome: 1; NC_003070.9 (20194712..20199193, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Genetic background and cis-organization regulate ALDH7B4 gene expression in Eutrema salsugineum: a promoter analysis case study.
Title: Genetic background and cis-organization regulate ALDH7B4 gene expression in Eutrema salsugineum: a promoter analysis case study.
a role of ALDHs as major contributors to the homeostasis of pyridine nucleotides in plants
Title: Aldehyde Dehydrogenases Function in the Homeostasis of Pyridine Nucleotides in Arabidopsis thaliana.
Overexpression of ATAF1 in Arabidopsis plants results in elevated expression of ALDH7B4 in seeds, seedlings, and mature plants, whereas ATAF1 knock-out mutant plants abolished the expression of ALDH7B4. This study implies that ATAF1 may confer stress tolerance by up-regulating the target gene ALDH7B4.
Title: The ATAF1 transcription factor is a key regulator of aldehyde dehydrogenase 7B4 (ALDH7B4) gene expression in Arabidopsis thaliana.
ALDH3I1 and ALDH7B4 are strongly induced by heat stress. Higher levels of ALDH7B4 accumulated in response to dehydration-heat, heat-salt and wounding-heat combination stress than in response to single stressors.
Title: The role of Arabidopsis aldehyde dehydrogenase genes in response to high temperature and stress combinations.
Plants that overexpressed the ALDH7B4 gene accumulated less soluble sugars, starch, and fatty acids and grew better than the wild-type after herbicide treatment.
Title: Induction of the PDH bypass and upregulation of the ALDH7B4 in plants treated with herbicides inhibiting amino acid biosynthesis.
The gene expression in selected Arabidopsis mutants demonstrated that osmotic stress-induced ALDH7B4 expression in leaves and seeds involves both ABA- and lipid-signalling components.
Title: Sequence and functional analyses of the aldehyde dehydrogenase 7B4 gene promoter in Arabidopsis thaliana and selected Brassicaceae: regulation patterns in response to wounding and osmotic stress.
Constitutive or stress-inducible expression of ALDH7B4 confers tolerance to osmotic and oxidative stress.
Title: Over-expression of different aldehyde dehydrogenase genes in Arabidopsis thaliana confers tolerance to abiotic stress and protects plants against lipid peroxidation and oxidative stress.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_104287.5

Supported by ESTs:

NM_179476.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables aldehyde dehydrogenase (NAD+) activity	ISS Inferred from Sequence or Structural Similarity more info
enables glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in aldehyde metabolic process	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within response to abscisic acid	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to desiccation	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to salt stress	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: aldehyde dehydrogenase 7B4

NP_175812.1

aldehyde dehydrogenase 7B4 (ALDH7B4); FUNCTIONS IN: 3-chloroallyl aldehyde dehydrogenase activity, oxidoreductase activity; INVOLVED IN: response to desiccation, response to salt stress, response to abscisic acid stimulus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Aldehyde/histidinol dehydrogenase (InterPro:IPR016161), Aldehyde dehydrogenase (InterPro:IPR015590), Aldehyde dehydrogenase, N-terminal (InterPro:IPR016162), Aldehyde dehydrogenase, conserved site (InterPro:IPR016160); BEST Arabidopsis thaliana protein match is: aldehyde dehydrogenase 5F1 (TAIR:AT1G79440.1); Has 58805 Blast hits to 58641 proteins in 2995 species: Archae - 475; Bacteria - 35443; Metazoa - 2491; Fungi - 2112; Plants - 1217; Viruses - 0; Other Eukaryotes - 17067 (source: NCBI BLink).

NP_849807.1

aldehyde dehydrogenase 7B4 (ALDH7B4); FUNCTIONS IN: 3-chloroallyl aldehyde dehydrogenase activity, oxidoreductase activity; INVOLVED IN: response to desiccation, response to salt stress, response to abscisic acid stimulus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Aldehyde/histidinol dehydrogenase (InterPro:IPR016161), Aldehyde dehydrogenase (InterPro:IPR015590), Aldehyde dehydrogenase, N-terminal (InterPro:IPR016162), Aldehyde dehydrogenase, conserved site (InterPro:IPR016160); BEST Arabidopsis thaliana protein match is: aldehyde dehydrogenase 5F1 (TAIR:AT1G79440.1); Has 58930 Blast hits to 58766 proteins in 3009 species: Archae - 476; Bacteria - 35564; Metazoa - 2491; Fungi - 2115; Plants - 1217; Viruses - 0; Other Eukaryotes - 17067 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

20194712..20199193 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_179476.3 → NP_849807.1 aldehyde dehydrogenase 7B4 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_849807.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q546B7, Q9SYG7

UniProtKB/TrEMBL

A0A178W3F2, A0A5S9WLT0

Conserved Domains (1) summary

PLN02315
Location:1 → 508

PLN02315; aldehyde dehydrogenase family 7 member
NM_104287.5 → NP_175812.1 aldehyde dehydrogenase 7B4 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_175812.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q546B7, Q9SYG7

UniProtKB/TrEMBL

A0A178W3F2, A0A5S9WLT0

Conserved Domains (1) summary

PLN02315
Location:1 → 508

PLN02315; aldehyde dehydrogenase family 7 member