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    Gltp glycolipid transfer protein [ Mus musculus (house mouse) ]

    Gene ID: 56356, updated on 27-Nov-2024

    Summary

    Official Symbol
    Gltpprovided by MGI
    Official Full Name
    glycolipid transfer proteinprovided by MGI
    Primary source
    MGI:MGI:1929253
    See related
    Ensembl:ENSMUSG00000011884 AllianceGenome:MGI:1929253
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110001F24Rik
    Summary
    Predicted to enable several functions, including ceramide 1-phosphate binding activity; ceramide 1-phosphate transfer activity; and identical protein binding activity. Predicted to be involved in ceramide transport and intermembrane lipid transfer. Predicted to be active in cytosol. Is expressed in several structures, including cerebral cortex ventricular layer; meninges; naris; and thymus primordium. Orthologous to human GLTP (glycolipid transfer protein). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in stomach adult (RPKM 119.7), lung adult (RPKM 84.5) and 26 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Gltp in Genome Data Viewer
    Location:
    5 F; 5 55.99 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (114807551..114828996, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (114669490..114690935, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 222, member A Neighboring gene STARR-positive B cell enhancer ABC_E8071 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:115047361-115047562 Neighboring gene predicted gene, 34844 Neighboring gene transient receptor potential cation channel, subfamily V, member 4 Neighboring gene STARR-positive B cell enhancer ABC_E2757 Neighboring gene STARR-positive B cell enhancer ABC_E9261 Neighboring gene STARR-seq mESC enhancer starr_14082 Neighboring gene predicted gene, 34931 Neighboring gene STARR-positive B cell enhancer ABC_E10341 Neighboring gene trichoplein, keratin filament binding Neighboring gene microRNA 7028

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Gene trapped (1) 
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ceramide 1-phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ceramide 1-phosphate transfer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables glycolipid binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables glycolipid binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables lipid binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables lipid binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables lipid transfer activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables lipid transfer activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in ceramide transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intermembrane lipid transfer IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intermembrane lipid transfer ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in intermembrane lipid transfer ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in response to immobilization stress IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    glycolipid transfer protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019821.2NP_062795.2  glycolipid transfer protein

      See identical proteins and their annotated locations for NP_062795.2

      Status: PROVISIONAL

      Source sequence(s)
      BC016584
      Consensus CDS
      CCDS19569.1
      UniProtKB/Swiss-Prot
      Q91YJ7, Q9CTK9, Q9JL62
      UniProtKB/TrEMBL
      Q3U011
      Related
      ENSMUSP00000012028.8, ENSMUST00000012028.14
      Conserved Domains (1) summary
      pfam08718
      Location:22166
      GLTP; Glycolipid transfer protein (GLTP)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      114807551..114828996 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)