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    Fam222b family with sequence similarity 222, member B [ Mus musculus (house mouse) ]

    Gene ID: 216971, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Fam222bprovided by MGI
    Official Full Name
    family with sequence similarity 222, member Bprovided by MGI
    Primary source
    MGI:MGI:2384939
    See related
    Ensembl:ENSMUSG00000037750 AllianceGenome:MGI:2384939
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9630020I17Rik
    Summary
    Predicted to be located in nucleoplasm. Is expressed in central nervous system and retina. Orthologous to human FAM222B (family with sequence similarity 222 member B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 11.6), ovary adult (RPKM 11.1) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Fam222b in Genome Data Viewer
    Location:
    11 B5; 11 46.74 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (77985516..78048165)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (78094690..78157339)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 57805 Neighboring gene microRNA 451a Neighboring gene microRNA 451b Neighboring gene Era like 12S mitochondrial rRNA chaperone 1 Neighboring gene STARR-seq mESC enhancer starr_30086 Neighboring gene U6 small nuclear RNA associated LSM6 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E10694 Neighboring gene STARR-seq mESC enhancer starr_30088 Neighboring gene TNF receptor associated factor 4 Neighboring gene STARR-positive B cell enhancer ABC_E8429 Neighboring gene STARR-positive B cell enhancer ABC_E9831 Neighboring gene NIMA (never in mitosis gene a)-related expressed kinase 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    2. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    3. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC28990

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM222B
    Names
    uncharacterized protein C17orf63 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001346762.2 → NP_001333691.1  protein FAM222B isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK047860, AL591070
      Consensus CDS
      CCDS83851.1
      UniProtKB/TrEMBL
      E9PXL0
      Related
      ENSMUSP00000126620.2, ENSMUST00000100782.4
      Conserved Domains (1) summary
      pfam15258
      Location:1 → 434
      FAM222A; Protein family of FAM222A

    2. NM_001364110.1 → NP_001351039.1  protein FAM222B isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL591070, AL669840
      Consensus CDS
      CCDS25089.1
      UniProtKB/Swiss-Prot
      Q3UV50, Q6P539, Q8VD11
      Related
      ENSMUSP00000121832.2, ENSMUST00000155571.2
      Conserved Domains (1) summary
      pfam15258
      Location:27 → 561
      FAM222A; Protein family of FAM222A

    3. NM_145430.3 → NP_663405.1  protein FAM222B isoform 1

      See identical proteins and their annotated locations for NP_663405.1

      Status: VALIDATED

      Source sequence(s)
      AK085728, AK141119, AL591070, BE332328
      Consensus CDS
      CCDS25089.1
      UniProtKB/Swiss-Prot
      Q3UV50, Q6P539, Q8VD11
      Related
      ENSMUSP00000073384.6, ENSMUST00000073705.12
      Conserved Domains (1) summary
      pfam15258
      Location:27 → 561
      FAM222A; Protein family of FAM222A

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      77985516..78048165
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030245839.2 → XP_030101699.1  protein FAM222B isoform X1

      UniProtKB/TrEMBL
      E9PXL0
      Conserved Domains (1) summary
      pfam15258
      Location:1 → 434
      FAM222A; Protein family of FAM222A
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6P539.2 GenPept UniProtKB/Swiss-Prot:Q6P539

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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