Replication interactions
Interaction |
Pubs |
HIV-1 replication is enhanced by PDE8A |
PubMed
|
shRNA knockdown of PDE8A decreases HIV-1 replication in primary monocytes; HIV-1 replication is enhanced by PDE8A |
PubMed
|
Knockdown of phosphodiesterase 8A (PDE8A) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells |
PubMed
|
Protein interactions
Protein |
Gene |
Interaction |
Pubs |
Tat
|
tat
|
HIV-1 Tat decreases the intracellular levels of cAMP and CREB ser-133 phosphorylation through a signal transduction pathway involving sequential activation of phosphatidylinositol 3-kinase, AKT, and cyclic nucleoside phosphodiesterases |
PubMed
|
Go to the HIV-1, Human Interaction Database