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    Fam161b family with sequence similarity 161, member B [ Mus musculus (house mouse) ]

    Gene ID: 217705, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Fam161bprovided by MGI
    Official Full Name
    family with sequence similarity 161, member Bprovided by MGI
    Primary source
    MGI:MGI:2443027
    See related
    Ensembl:ENSMUSG00000021234 AllianceGenome:MGI:2443027
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9330169D17; 9830169C18Rik
    Summary
    Predicted to be involved in cilium organization. Predicted to be located in cytoplasmic microtubule. Predicted to colocalize with cilium. Orthologous to human FAM161B (FAM161 centrosomal protein B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E18 (RPKM 4.6), CNS E14 (RPKM 4.6) and 22 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Fam161b in Genome Data Viewer
    Location:
    12 D1; 12 39.17 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (84392088..84408633, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (84345309..84361860, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10765 Neighboring gene prostaglandin reductase 2 Neighboring gene zinc finger protein 410 Neighboring gene LSM6 homolog, U6 small nuclear RNA associated pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E1445 Neighboring gene coenzyme Q6 monooxygenase Neighboring gene ectonucleoside triphosphate diphosphohydrolase 5 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:85729760-85729947 Neighboring gene STARR-positive B cell enhancer ABC_E8493 Neighboring gene basal body orientation factor 1 Neighboring gene ring finger protein 113A2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Sang L, et al. Cell, 2011 May 13. PMID 21565611, Free PMC Article
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cilium organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    colocalizes_with cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasmic microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasmic microtubule ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM161B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358283.2 → NP_001345212.1  protein FAM161B

      Status: VALIDATED

      Source sequence(s)
      AC120402, AC159649
      Consensus CDS
      CCDS26043.1
      UniProtKB/Swiss-Prot
      Q8BQX8, Q8BSL9, Q8CB59, Q8CBZ3
      Related
      ENSMUSP00000070407.3, ENSMUST00000065536.9
      Conserved Domains (1) summary
      pfam10595
      Location:168 → 535
      UPF0564; Uncharacterized protein family UPF0564

    2. NM_172581.4 → NP_766169.1  protein FAM161B

      See identical proteins and their annotated locations for NP_766169.1

      Status: VALIDATED

      Source sequence(s)
      AC120402, AC159649
      Consensus CDS
      CCDS26043.1
      UniProtKB/Swiss-Prot
      Q8BQX8, Q8BSL9, Q8CB59, Q8CBZ3
      Related
      ENSMUSP00000021659.2, ENSMUST00000021659.2
      Conserved Domains (1) summary
      pfam10595
      Location:168 → 535
      UPF0564; Uncharacterized protein family UPF0564

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      84392088..84408633 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036157324.1 → XP_036013217.1  protein FAM161B isoform X1

      Conserved Domains (1) summary
      pfam10595
      Location:168 → 529
      UPF0564; Uncharacterized protein family UPF0564

    RNA

    1. XR_003950036.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8CB59.1 GenPept UniProtKB/Swiss-Prot:Q8CB59

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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