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    OR56A5 olfactory receptor family 56 subfamily A member 5 [ Homo sapiens (human) ]

    Gene ID: 390084, updated on 10-Dec-2024

    Summary

    Official Symbol
    OR56A5provided by HGNC
    Official Full Name
    olfactory receptor family 56 subfamily A member 5provided by HGNC
    Primary source
    HGNC:HGNC:14792
    See related
    Ensembl:ENSG00000188691 AllianceGenome:HGNC:14792
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    OR56A5P
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Mar 2009]
    Orthologs
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    Genomic context

    See OR56A5 in Genome Data Viewer
    Location:
    11p15.4
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (5967553..5968494, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (6026055..6026996, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (5988783..5989724, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112268071 Neighboring gene olfactory receptor family 52 subfamily E member 5 Neighboring gene olfactory receptor family 52 subfamily Q member 1 pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:5943920-5945119 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:5949120-5950319 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:5958637-5959836 Neighboring gene olfactory receptor family 56 subfamily A member 3 Neighboring gene uncharacterized LOC124902621 Neighboring gene olfactory receptor family 52 subfamily L member 1

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    olfactory receptor 56A5
    Names
    olfactory receptor, family 56, subfamily A, member 5 pseudogene

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001146033.1NP_001139505.1  olfactory receptor 56A5

      See identical proteins and their annotated locations for NP_001139505.1

      Status: VALIDATED

      Source sequence(s)
      AC025016
      Consensus CDS
      CCDS73248.1
      UniProtKB/Swiss-Prot
      P0C7T3
      UniProtKB/TrEMBL
      A0A126GWP3
      Related
      ENSP00000481594.1, ENST00000532411.2
      Conserved Domains (2) summary
      pfam00001
      Location:45295
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:45310
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      5967553..5968494 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      6026055..6026996 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)