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    PUM1 pumilio 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817469, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PUM1
    Official Full Name
    pumilio 1
    Primary source
    TAIR:AT2G29200
    Locus tag
    AT2G29200
    See related
    Araport:AT2G29200
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    APUM1; F16P2.42; F16P2_42; pumilio 1
    Summary
    Encodes a member of the Arabidopsis Pumilio (APUM) proteins containing PUF domain (eight repeats of approximately 36 amino acids each). PUF proteins regulate both mRNA stability and translation through sequence-specific binding to the 3' UTR of target mRNA transcripts.
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    Genomic context

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    See PUM1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    11
    Sequence:
    Chromosome: 2; NC_003071.7 (12548931..12553711, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pumilio 2 Neighboring gene splicing factor PWI domain-containing protein Neighboring gene Concanavalin A-like lectin protein kinase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular characterization of Arabidopsis thaliana PUF proteins--binding specificity and target candidates. Francischini CW, et al. FEBS J, 2009 Oct. PMID 19682068
    2. In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings. Reichel M, et al. Plant Cell, 2016 Oct. PMID 27729395, Free PMC Article
    3. Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. Ito J, et al. J Proteome Res, 2011 Apr 1. PMID 21166475
    4. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
    5. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    NM_128476.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pumilio 1
    NP_180483.1
    • pumilio 1 (PUM1); FUNCTIONS IN: RNA binding, binding; LOCATED IN: cellular_component unknown; EXPRESSED IN: cultured cell; CONTAINS InterPro DOMAIN/s: Nucleic acid binding NABP (InterPro:IPR012940), Pumilio RNA-binding repeat (InterPro:IPR001313), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: pumilio 3 (TAIR:AT2G29140.1); Has 3905 Blast hits to 1986 proteins in 235 species: Archae - 0; Bacteria - 0; Metazoa - 808; Fungi - 1312; Plants - 896; Viruses - 0; Other Eukaryotes - 889 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      12548931..12553711 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001336203.1 → NP_001324547.1  pumilio 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZW07
      UniProtKB/TrEMBL
      A0A7G2EG09

    2. NM_128476.3 → NP_180483.1  pumilio 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180483.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZW07
      UniProtKB/TrEMBL
      A0A7G2EG09
      Conserved Domains (3) summary
      cd07920
      Location:626 → 946
      Pumilio; Pumilio-family RNA binding domain
      COG5099
      Location:212 → 952
      COG5099; RNA-binding protein of the Puf family, translational repressor [Translation, ribosomal structure and biogenesis]
      pfam07990
      Location:269 → 628
      NABP; Nucleic acid binding protein NABP
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZW07.1

    Gene LinkOut

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